PT  - JOURNAL ARTICLE
AU  - Joaquim, Andrei Fernandes
AU  - Schroeder, Gregory D.
AU  - Vaccaro, Alexander R.
TI  - Traumatic Atlanto-Occipital Dislocation—A Comprehensive Analysis of All Case Series Found in the Spinal Trauma Literature
AID  - 10.14444/8095
DP  - 2021 Aug 01
TA  - International Journal of Spine Surgery
PG  - 724--739
VI  - 15
IP  - 4
4099  - https://www.ijssurgery.com/content/15/4/724.short
4100  - https://www.ijssurgery.com/content/15/4/724.full
SO  - Int J Spine Surg2021 Aug 01; 15
AB  - Background: Traumatic atlanto-occipital dislocation (TAOD) is one of the most devastating traumatic injuries, generally associated with immediate death after high-energy trauma. The aim of this study was to perform a systematic literature review of all cases series of TAOD and present the current state of this entity.Methods: A systematic literature review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only case series with at least 5 cases were included in the analysis. We focused on survival rates, diagnostic methods, delays in diagnosis, outcomes, and cases successfully treated nonoperatively.Results: A total of 17 articles were included (16 retrospective and 1 prospective study) with 341 patients. Six studies included pediatric patients only. The mean Glasgow Coma Scale at admission was ≤8 in all studies. Many different diagnostic criteria were used, but none of them had high accuracy. The overall mortality rate was 34.8%, but the studies' designs were heterogeneous (some included only survivors). A high rate of concomitant traumatic brain injury was documented in some studies. We found it interesting that some patients were treated with cervical immobilization (37/341; 10.8%), which was generally used in less unstable injuries; however, the majority of patients were managed with an occipito-cervical fusion (193/341; 56.5%).Conclusions: TAOD is a devastating traumatic injury, with a high mortality rate. An MRI may be recommended when there are subtle findings of TAOD and a normal computed tomography scan, such as subarachnoid hemorrhage in the posterior fossa, upper cervical injuries, or consistent neurological findings. Further studies are necessary to identify patients with mild MRI findings and TAOD that may be managed nonoperatively.