PT - JOURNAL ARTICLE AU - Sriphirom, Pornpavit AU - Siramanakul, Chaiyaporn AU - Sumritsopak, Manoch AU - Chokviriyaprasert, Parinya AU - Uttamo, Nantawat AU - Songchou, Kittinon TI - Clinical Outcomes of Interlaminar Percutaneous Endoscopic Uniportal Pars Decompression for Lumbar Spondylolysis AID - 10.14444/8413 DP - 2022 Dec 06 TA - International Journal of Spine Surgery PG - 8413 4099 - https://www.ijssurgery.com/content/early/2022/12/06/8413.short 4100 - https://www.ijssurgery.com/content/early/2022/12/06/8413.full AB - Background To evaluate the clinical and radiological outcomes of a novel full endoscopic procedure performed via an interlaminar approach to decompress entrapped nerve roots in patients with lumbar spondylolysis.Methods Patients who underwent interlaminar percutaneous endoscopic pars decompression were included in this retrospective cohort study. Patients with back pain and dynamic lumbar instability were excluded from the study. Clinical parameters related to outcomes, including the Oswestry Disability Index (ODI) and visual analog scale (VAS) for leg pain, were assessed before and after surgery. The radiological outcomes, vertebral slippage percentage, and motion radiographs were evaluated preoperatively and postoperatively.Results Of the 11 patients included in the study, 5 had spondylolysis alone, 1 of whom had spondylolysis at L3-L4 and L4-L5, and 4 of whom had it at L5-S1; and 6 patients had spondylolysis in combination with spondylolisthesis, of whom 4 had involvement at L5-S1, 1 had involvement at L4-L5, and 1 had involvement at L3-L4. At a mean follow-up period of 22.64 months, 63.3% of patients achieved more than 50% improvement in ODI score and 90.91% of patients achieved more than 50% improvement in VAS score. Spondylolysis with vertebral slippage had inferior ODI improvement outcomes as compared with spondylolysis alone, but the VAS was not significantly different. No significant difference was observed on the slippage percentage observed between the pre- and postoperative periods. However, 1 patient experienced vertebral slippage after surgery, but fusion surgery was not required.Conclusions Interlaminar percutaneous endoscopic pars decompression is a safe and successful treatment for patients with stable lumbar spondylolysis and nerve root compression. Even in situations in which vertebral slippage occurs, spinal fusion may not be the best option for all patients with lumbar spondylolysis.Clinical Relevance The interlaminar percutaneous endoscopic pars decompression is a safe and successful procedure for treatment of patients with stable lumbar spondylolysis and nerve root compression.Level of Evidence 4.