PT - JOURNAL ARTICLE AU - Brendan F. Judy AU - Jovanna A. Tracz AU - Safwan Alomari AU - Timothy F. Witham TI - Patient Optimization for the Prevention of Proximal Junctional Kyphosis AID - 10.14444/8510 DP - 2023 Jun 15 TA - International Journal of Spine Surgery PG - 8510 4099 - https://www.ijssurgery.com/content/early/2023/06/15/8510.short 4100 - https://www.ijssurgery.com/content/early/2023/06/15/8510.full AB - Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are well-recognized challenges of surgery for adult spinal deformity (ASD). Multiple risk factors have been identified for PJK/PJF, including osteoporosis, frailty, neurodegenerative disease, obesity, and smoking. Several surgical techniques to mitigate risk of PJK/PJF have been identified; however, patient optimization is also critical. This review summarizes the data behind these 5 risk factors (osteoporosis, frailty, neurodegenerative disease, obesity, and smoking) and details the related recommendations for patients undergoing surgery for ASD.