PT  - JOURNAL ARTICLE
AU  - Alelaumi, Ahmad
AU  - Alfawareh, Mohammad
AU  - Althunibat, Ismail
AU  - Al-Ibraheem, Akram
AU  - Barakat, Fareed
TI  - Diffuse Sarcoidosis Presenting as Metastatic Malignant Disease-Like Picture: A Case Report
AID  - 10.14444/8523
DP  - 2023 Jul 21
TA  - International Journal of Spine Surgery
PG  - 8523
4099  - https://www.ijssurgery.com/content/early/2023/07/20/8523.short
4100  - https://www.ijssurgery.com/content/early/2023/07/20/8523.full
AB  - Background Sarcoidosis is a chronic inflammatory condition characterized by the formation of granulomas, which can impact various organs and tissues throughout the body. It frequently affects the lungs and mediastinal lymph nodes. The presence of multiple lytic lesions in the spine can be concerning, as it may indicate an undiagnosed or advanced metastatic malignancy. We present an unusual and interesting case of sarcoidosis in which the patient had multiple lytic lesions in the vertebrae, which resembled the presentation of metastatic malignant disease.Case Description A 46-year-old woman with no known medical history presented to our cancer center complaining of neck pain and bilateral shoulder pain. After conducting extensive investigations, an atypical manifestation of sarcoidosis was identified. The patient was administered corticosteroids, which effectively managed the disease and resulted in a substantial improvement in her symptoms.Conclusions Before considering surgical intervention or radiotherapy for cases involving multiple lytic lesions in the spine with an unknown primary cause, it is essential to conduct a comprehensive diagnostic evaluation. This thorough work-up is necessary to establish a clear diagnosis. If the patient’s neurological condition permits, a complete assessment can help prevent substantial morbidity. In certain cases, a patient’s condition may involve an atypical manifestation of pathologies that are not related to metastatic diseases, suggesting that simpler treatment approaches might be adequate.