RT Journal Article
SR Electronic
T1 Demineralized Bone Matrix and Fibers in Spinal Fusion
JF International Journal of Spine Surgery
JO Int J Spine Surg
FD International Society for the Advancement of Spine Surgery
SP 8558
DO 10.14444/8558
A1 Wang, Joshua L.
A1 Eaton, Ryan G.
A1 Harrigan, Markus E.
A1 Munjal, Vikas
A1 Sette, Katelyn N.
A1 Wilson, Seth B.
A1 Grossbach, Andrew J.
YR 2023
UL https://www.ijssurgery.com/content/early/2023/12/21/8558.abstract
AB Formation of bony fusion after arthrodesis depends on osteoinduction, osteoconduction, and osteogenesis. Traditionally, the patient’s own bone, or autograft, has been used to provide biological material necessary for these steps. However, the amount of autograft obtainable is often inadequate. Modern spine surgery has adopted the use of many autograft extenders or replacements, such as demineralized bone matrix or fibers. The present article covers the history of bone grafting, the production and technical details of demineralized bone matrix, and the evidence supporting its use in spine fusions.