PT - JOURNAL ARTICLE AU - Shen, Minjie AU - Niu, Junjie AU - Zhou, Haifei AU - Meng, Qian AU - Gan, Minfeng AU - Yang, Huilin TI - Adjacent disc height reduction and clinical outcome after intradiscal cement leakage AID - 10.14444/3034 DP - 2016 Jan 01 TA - International Journal of Spine Surgery PG - 34 VI - 10 4099 - https://www.ijssurgery.com/content/10/34.short 4100 - https://www.ijssurgery.com/content/10/34.full SO - Int J Spine Surg2016 Jan 01; 10 AB - Objective The purpose of this study is to evaluate the effect of intradiscal cement leakage on the height of adjacent cement-containing discs and the resulting clinical efficacy after kyphoplasty.Methods A total of 124 patients were included and classified into two groups: group A included 20 patients with intradiscal leakage, and group B contained 104 patients without intradiscal leakage. The mean follow-up time was 20.56±3.51 months. The height of the corresponding discs in both groups was measured using Farfan’s method. Clinical efficacy was assessed using the Visual Analog Scale and Oswestry Disability Index scores at each follow-up time.Results The anterior disc height, posterior disc height and Farfan Index significantly decreased in both groups at last follow-up. The disc height reduction was 9.19±2.89% in group A and 3.88±2.70% in group B, which was significantly different between the groups (P<0.01). The disc height reduction rate was 29.39±7.90% in group A and 12.75±8.18% in group B, which was also a statistically significant difference (P<0.01). The VAS and ODI scores improved significantly after surgery and maintained at last follow-up, and there was no statistically significant difference between Groups A and B.Conclusion Intradiscal cement leakage was associated with the degeneration of cement-containing disc but did not reduce the clinical efficacy at early stages.