PT - JOURNAL ARTICLE AU - KARABULUT, CEM AU - AYHAN, SELIM AU - YUKSEL, SELCEN AU - NABIYEV, VUGAR AU - VILA-CASADEMUNT, ALBA AU - PELLISE, FERRAN AU - ALANAY, AHMET AU - PEREZ-GRUESO, FRANCISCO JAVIER SANCHEZ AU - KLEINSTUCK, FRANK AU - OBEID, IBRAHIM AU - ACAROGLU, EMRE AU - EUROPEAN SPINE STUDY GROUP TI - Adult Spinal Deformity Over 70 Years of Age: A 2-Year Follow-Up Study AID - 10.14444/6046 DP - 2019 Aug 01 TA - International Journal of Spine Surgery PG - 336--344 VI - 13 IP - 4 4099 - https://www.ijssurgery.com/content/13/4/336.short 4100 - https://www.ijssurgery.com/content/13/4/336.full SO - Int J Spine Surg2019 Aug 01; 13 AB - Background: Treatment of adult spinal deformity (ASD) in elderly patients remains controversial. The aim of this study was to identify the factors leading to the surgical treatment by comparing the baseline characteristics of operative versus nonoperative patients, to evaluate the safety and efficacy of surgery, and to compare operative and nonoperative management of elderly ASD patients at the end of the 2-year follow-up period.Methods: Retrospective review of a multicenter, prospective ASD database was performed. Patients over 70 years of age with ASD who were scheduled to undergo surgical treatment and who were treated and/or followed without surgical intervention participated in the study. Demographic, clinical, surgical, and radiological characteristics and health-related quality-of-life (HRQOL) (Core Outcome Measures Index [COMI], Oswestry Disability Index [ODI], Short-Form-36 Mental Component Summary [SF-36 MCS], Short-Form-36 Physical Component Summary [SF36-PCS], and Scoliosis Research Society-22 [SRS-22]) parameters of such group of patients were evaluated pre- and posttreatment.Results: A total 90 patients (females: 71, males: 29; operative: 61, nonoperative: 29) made up the study group. The comparison between the operative and the nonoperative groups at baseline showed statistical significance for all the HRQOL parameters and the major coronal Cobb angle (P < .05). The calculated optimal cutoff values to diverge operative and nonoperative groups for COMI, ODI, SF-36 PCS, and SRS-22 were 5.7, 37.0, 37.5, and 3.2, respectively (P < .05). All operative patients were treated with posterior surgery. Overall, 135 complications (71 major, 64 minor) and 1 death were observed. Surgically treated patients were found to be improved both clinically and in HRQOL parameters 2 years after surgery for all HRQOL parameters except SF-36 MCS, even in the presence of complications (P < .05), while nonoperative patients have not changed or deteriorated at the end of 2 years.Conclusions: Despite a relatively high incidence of complications, the likelihood of achieving a clinically significant and relevant HRQOL improvement was superior for patients who were treated surgically in the present population.