PT - JOURNAL ARTICLE AU - BENJAMIN C. MAYO AU - DUSTIN H. MASSEL AU - ALEM YACOB AU - ANKUR S. NARAIN AU - FADY Y. HIJJI AU - NATHANIEL W. JENKINS AU - JAMES M. PARRISH AU - KRISHNA D. MODI AU - WILLIAM W. LONG AU - NADIA M. HRYNEWYCZ AU - THOMAS S. BRUNDAGE AU - KERN SINGH TI - A Review of Vitamin D in Spinal Surgery: Deficiency Screening, Treatment, and Outcomes AID - 10.14444/7059 DP - 2020 Jun 01 TA - International Journal of Spine Surgery PG - 447--454 VI - 14 IP - 3 4099 - http://ijssurgery.com//content/14/3/447.short 4100 - http://ijssurgery.com//content/14/3/447.full SO - Int J Spine Surg2020 Jun 01; 14 AB - In this review, we discuss the demonstrated value of vitamin D in bone maintenance, fracture resistance, spinal health, and spine surgery outcomes. Despite this, the effect of vitamin D levels in spine surgery has not been well described. Through this review of literature, several conclusions were drawn. First, despite the fact that a high number of spine surgery patients are vitamin D deficient, screening is not commonly performed. Second, adequate vitamin D levels will not be achieved in a majority of these patients without supplementation. Last, inadequate vitamin D levels may increase the risk of pseudarthrosis. Given these findings, we suggest that many patients undergoing spinal surgery could be treated with vitamin D supplementation prior to surgery without the need for confirmatory testing for vitamin D deficiency. This is a more cost-effective method than screening all patients. However, future randomized trials and cost-effectiveness analyses are needed to determine the ultimate effects of vitamin D supplementation on clinical morbidity and surgical outcomes.