RT Journal Article SR Electronic T1 A Review of Vitamin D in Spinal Surgery: Deficiency Screening, Treatment, and Outcomes JF International Journal of Spine Surgery JO Int J Spine Surg FD International Society for the Advancement of Spine Surgery SP 447 OP 454 DO 10.14444/7059 VO 14 IS 3 A1 BENJAMIN C. MAYO A1 DUSTIN H. MASSEL A1 ALEM YACOB A1 ANKUR S. NARAIN A1 FADY Y. HIJJI A1 NATHANIEL W. JENKINS A1 JAMES M. PARRISH A1 KRISHNA D. MODI A1 WILLIAM W. LONG A1 NADIA M. HRYNEWYCZ A1 THOMAS S. BRUNDAGE A1 KERN SINGH YR 2020 UL http://ijssurgery.com//content/14/3/447.abstract AB In this review, we discuss the demonstrated value of vitamin D in bone maintenance, fracture resistance, spinal health, and spine surgery outcomes. Despite this, the effect of vitamin D levels in spine surgery has not been well described. Through this review of literature, several conclusions were drawn. First, despite the fact that a high number of spine surgery patients are vitamin D deficient, screening is not commonly performed. Second, adequate vitamin D levels will not be achieved in a majority of these patients without supplementation. Last, inadequate vitamin D levels may increase the risk of pseudarthrosis. Given these findings, we suggest that many patients undergoing spinal surgery could be treated with vitamin D supplementation prior to surgery without the need for confirmatory testing for vitamin D deficiency. This is a more cost-effective method than screening all patients. However, future randomized trials and cost-effectiveness analyses are needed to determine the ultimate effects of vitamin D supplementation on clinical morbidity and surgical outcomes.