RT Journal Article SR Electronic T1 Degenerative Adult Cervical Kyphosis With Secondary Diagnosis Codes Are Associated With Higher Cost and Complications After Spinal Fusion: A Medicare Database Study JF International Journal of Spine Surgery JO Int J Spine Surg FD International Society for the Advancement of Spine Surgery SP 8003 DO 10.14444/8003 A1 Jain, Nikhil A1 Malik, Azeem T. A1 Phillips, Frank M. A1 Khan, Safdar N. A1 Yu, Elizabeth YR 2021 UL https://www.ijssurgery.com/content/early/2021/02/10/8003.abstract AB Background Adult cervical deformity (ACD) is a potentially debilitating condition resulting from kyphosis, scoliosis, or both, of the cervical spine. Conditions such as ankylosing spondylitis, rheumatoid arthritis, Parkinson's disease, and neuromuscular diseases are particularly known to cause severe deformities. We describe the 90-day cost and complications associated with spinal fusion for ACD using International Classification of Diseases (ICD) coding terminology and study if secondary diagnoses associated with potential for severe deformity affect the cost and complication profile of ACD surgery.Methods Medicare data were used to study hospital costs and complications within 90 days after primary cervical fusion for ACD in 2 cohorts matched by demographics and comorbidity burden: (1) patients with diagnoses of secondary pathology (SP) known to cause severe deformity and (2) without SP. Univariate and multiple-variable analyses to study incidence of complications, readmission, and costs within 90 days were done.Results A total of 2900 patients in matched cohorts of 1450 each were included. The mean index hospital payment ($26 545 ± $25 968 versus $22 991 ± $21 599) and length of stay (4.8 ± 5.6 versus 3.9 ± 4.5 days) was significantly (P < .01) higher in ACD patients with SP. On adjusted analysis, the risk of procedure-related complications was higher (odds ratio [OR] = 1.47, 95% confidence interval [CI], 1.18–1.83) in patients with SP than those without SP, but not readmission (OR = 1.04, 95% CI, 0.82–1.32) or refusion (OR = 0.95, 95% CI, 0.45–2.0) within 90 days. The cost profile of complications, readmission, and refusion has been given.Conclusions ACD patients with secondary diagnosis codes such as inflammatory arthropathy or neuromuscular pathology incur higher 90-day costs due to the inherent requirement of bigger fusions and higher risk of peri-operative complications, but with similar risk of readmission and refusion as those without SP.Level of Evidence 3.Clinical Relevance With evolving health care reforms and payment models, knowledge of conditions associated with higher expenditure after elective spine surgical procedures will be beneficial to providers and payors for appropriate risk stratification.