Summary comparing values from 3 different Food and Drug Administration investigational device exemption studies including ProDisc-C, Mobi-C, and M6-C.
| Study and Disc | Mean Blood Loss | Surgical Time | Reduction in NDI | Reduction in VAS Neck Pain | Reduction in VAS Arm Pain | Rates of Reoperation | ASD |
|
Murrey et al25 | |||||||
| ProDisc-C (n = 106) | 83.5 mL | 107 min | 32.5% | 4.6 cm | 4.3 cm | 1.90% | a |
| ACDF (n = 103) | 63.5 mL | 98.7 min | 31.7% | 4.3 cm | 4.4 cm | 8.50% | a |
| Davis et al26 | |||||||
| Mobi-C (n = 225) | a | a | 36.5% | 5.4 cm | 5.6 cm | 4.00% | 41.50% |
| ACDF (n = 105) | a | a | 28.5% | 4.8 cm | 5.3 cm | 15.20% | 85.90% |
| Sasso et al27 | |||||||
| M6-C (n = 83) | 31 mL | 81 min | 41.8% | 5.9 cm | 6.9 cm | 0.00% | a |
The reductions in Neck Disability Index (NDI) and visual analog scale (VAS) measure the difference between the value measured prior to surgery and the value measured at 2 years postsurgery.
aData missing where unavailable.
ACDF, anterior cervical discectomy and fusion; ASD, adjacent segment disease.