Table

Summary of patients with seizure-induced spinal fractures.

Author, YearAge, y (Sex)SymptomsCause of SeizuresEpilepsy TreatmentNumber SeizuresLevel of SpineAO Fracture TypeEvolution TimeDual-Energy X-ray AbsorptiometryAssociated ConditionsTreatmentOutcome
Lim & Shim, 202137 50 (M)LBP
Paraparesis
Hepatic cirrhosisNoMultipleL2A41 dOsteoporosisEncephalopathy360° T2-L4 stabilizationPartial recovery
Bosco et al, 202036 52 (M)LBP
Paraparesis
Idiopathic
First seizure
No1L1Burst A44 moNoT11-L3 instrumentationComplete recovery
Robichaud et al, 20205
Case 1
Case 2
71(M)
53 (M)
LBP
Paraparesis
LBP
Paraparesis
Intracranial meningioma
Idiopathic
No
No
1
1
L1
L1
Burst A4
Burst A4
1 wk
NA
No
No
Intracranial meningioma
Scapular fractures
Laminectomies T11-L3 stabilization
Decompression T11-L3 stabilization
Partial recovery
Partial recovery
Grzonka et al, 20196 49 (M)Interscapular painIdiopathicNoMultipleT4A11 dNoScapular fracturesConservativeComplete recovery
Hurley et al, 20197 47 (F)Neck painGelastic seizureCarbamaze pine + lamotrigineNAC2Hangman type II1 wkNoNAOccipitocervical fusionComplete recovery
Smith et al, 20178 44 (F)Dorsal painVenlafaxine overdoseNo1T8Burst A41 wkNoDepressionT7-T11 stabilizationComplete recovery
Stilwell et al, 20169 28 (M)Dorsal painIdiopathic epilepsyLamotrigine 1 y1T6-T7A110 dNormalConservative analgesicsComplete recovery
Gill et al, 201510 61 (F)Dorsal painNANoMultipleT6T6 burst A4
L5 A1
NoSternal fracture, bilateral humerus fractures, femur fractureT4-T8 stabilization
Lumbar conservative
Complete recovery
Moscote-Salazar et al, 201511 46(M)LBPNANANAL2A22 dNoPosterior fusionComplete recovery
Atalar et al, 201512 49 (M)Dorsal painIdiopathic, first seizureNo1T5-T8A11 dOsteoporosisType 1 diabetesConservative braceComplete recovery
Ali et al, 201513 52 (M)LBPBrain tumorNoNAL3A2NoShoulders dislocationConservativeNA
Uvaraj et al, 201414 18(M)Dorsal painIdiopathicNo1T5-T8A13 dNoNoBrace, conservativeComplete recovery
Majkowska et al, 201415 21 (F)LBPHypoglycemiaNo1T12A411 moOsteopeniaType 1 diabetesSurgery stabilizationNA
Ghayem Hasankhani et al, 201316 42 (M)LBPNANA1L2-3-4A1NANormalNoBrace, conservativeComplete recovery
Rahimiza- deh et al, 201217 20 (M)LBP Hypoesthesia lower limbsTramadol overdoseNo1T12Burst A41 wkNoT10-L2 stabilizationComplete recovery
Alian, 201118 35 (F)LBPIdiopathic epilepsyNo1T12Burst A42 dNoStabilization T11-L1NA
Malik et al, 201119 42 (F)LBPHypoglycemiaNo1L2Burst A35 dNoDiabetesBrace, conservativeComplete recovery
Sharma et al, 201120 36 (M)LBP
Cauda equina syndrome
Idiopathic epilepsyPhenytoin1L1
L2
Burst A4
A1
1 dNoHumeral fractureSurgery (no specified)Partial recovery
Napier and Nolan, 201121 28 (M)LBP
Paraplegia
Idiopathic epilepsyNAMultipleL1Burst A41 dNoStabilization T12-L2 LaminectomyPartial recovery
Is et al, 200922 62 (F)LBPIdiopathicNo1L1Burst A43 wkNoRheumatoid arthritisL1 corpectomy
Stabilization
Complete recovery
Kalaci et al, 200823 11 (M)Dorsal painIsoniazid intoxicationNoMultipleT5Burst A31 dNormalConservative braceComplete recovery
Mehlhorn et al, 200724 45 (M)LBPIdiopathic epilepsyNo1L2
L4
A2
A4
1 dOsteopeniaL1-L5 stabilizationNA
Shin et al, 200725
Case 1
Case 2
29 (M)34 (F)LBP
Paraparesis
LBP
Brain tumor
Brain tumor
No
No
11L2-L3
L2
Burst A3
Burst A3
1 d1 dOsteoporosis
Osteopenia
Shoulder dislocationAnterior L2-4 stabilization
Conservative
Complete recovery
Complete recovery
Roohi and Fox, 200626 35 (M)Cauda equina syndromeUnknown causeNo1L1Burst A32 dNoL1-3 stabilizationComplete recovery
Perry and Atkinson, 200627 42 (M)Dorsal painUnknownNo1T6-7-8A1NANoDislocation shouldersConservativeNA
Gnanalin- gham et al, 200428 26(M)Dorsal painFirst seizureNo1T5-6A11 dNoHistory of lupus
Steroids use
KyphoplastyComplete recovery
Takahashi et al, 200229 34 (M)Dorsal painIdiophatic epilepsyMultiple drugs1T6-7T6 A1
T7 A4
2 wkNormalCorpectomy stabilization T5-8Complete recovery
Torreggiani et al, 200130 75 (MFNeck painIdiopathic epilepsyNA1C2 dens fractureType 2 odontoid fracture
C1 fracture
1 dNoAnterior C2 screwPartial recovery
Kumar and Freeman, 199931
Case 1
Case 2
44 (M)34 (M)Neck pain
Quadriplegia
Neck pain
Quadriparesis
Idiopathic epilepsy
Idiopathic epilepsy
Phenytoin valproate
Phenytoin
NA
Multiple
C3-4
C3
C3-4 listesis
C3
Canal narrowing
1 d
1 d
No
No
360 Stabilization
Laminectomy
Partial recovery
Partial recovery
Aboukasm and Smith, 199732
Case 1
Case 2
21 (M)
36 (M)
Dorsal pain
Dorsal pain
Idiopathic epilepsy
Idiopathic epilepsy
No
No
11T7-8-9
T5-6
A1
A1
1 wk
1 d
No
No
Conservative
Conservative
NA
NA
Youssef et al, 199533 35 (M)LBPClozapine useNo1L1-L2L1 A4
L2 A1
5 dNoschizophreniaSurgery
Stabilization
Complete recovery
McCullen and Brown, 19941 41 (F)Dorsal painAmoxapine intoxicationNo1T6-T8T7 A41 wkNoHumeral fractureAnterior corpectomy T7 stabilization T4-10 posteriorComplete recovery
Gräbe, 198834 39 (M)LBPNANo1L5-S1Lumbosacral dislocationNANoAnterior lumbosacral fusionComplete recovery
Nabarro, 198535 48 (M)Dorsal painHypoglycemiaNo1T3-T4A11 dNoConservativeNA
  • LBP, low back pain; NA, not available.