Table 1

Baseline demographics of patients with opioid use disorder and comparison cohort undergoing lumbar spine laminectomy.

Demographics	Opioid Use Disorder		Comparison Cohort		P Value
Demographics	n	%	n	%	P Value
Age, y					<0.0001
<64	1977	56.24	14,522	11.33
65–69	686	19.52	34,910	27.25
70–74	409	11.64	32,494	25.36
75–79	252	7.17	25,603	19.98
80–84	138	3.93	14,680	11.46
>85	53	1.51	5911	4.61
Sex					<0.0001
Female	2011	57.21	62,253	48.59
Male	1504	42.79	65,867	51.41
Comorbidities
Alcohol use disorder	772	21.96	5368	4.19	<0.0001
Arrhythmias	1607	45.72	48,035	37.49	<0.0001
BMI 19–24 kg/m²	128	3.64	2023	1.58	<0.0001
BMI 25–29 kg/m²	214	6.09	4277	3.34	<0.0001
BMI 30–39 kg/m²	614	17.47	12,646	9.87	<0.0001
BMI 40–70 kg/m²	296	8.42	4322	3.37	<0.0001
Congestive heart failure	1081	30.75	27,085	21.14	<0.0001
Coagulopathy	668	19.00	16,026	12.51	<0.0001
Depressive disorders	2699	76.79	40,359	31.50	<0.0001
Diabetes mellitus	1729	49.19	52,110	40.67	<0.0001
Hypertension	3172	90.24	114,339	89.24	0.001
Hypothyroidism	1374	39.09	40,344	31.49	<0.0001
Iron deficiency anemia	2184	62.13	54,887	42.84	<0.0001
Liver failure	802	22.82	10,566	8.25	<0.0001
Neurological deficits	869	24.72	17,268	13.48	<0.0001
Peptic ulcer disease	649	18.46	12,160	9.49	<0.0001
Peripheral vascular disease	1455	41.39	46,191	36.05	<0.0001
Renal failure	340	9.67	7562	5.90	<0.0001
Rheumatoid arthritis	1466	41.71	26,868	20.97	<0.0001
Valvular disorders	1157	32.92	33,986	26.53	<0.0001
Pathologic weight loss	449	12.77	6939	5.42	<0.0001
Elixhauser Comorbidity Index, mean	9		4		<0.0001