Case | Indication for Surgery | Prior Treatment | Levels of Disc Space and Bone Involvement | Levels of Fixation Above | Levels of Fixation Below | Organism | IV Antibiotic Type and Duration | Oral Antibiotic Type and Duration |
1 | Osteomyelitis/discitis and bony instability | IV antibiotics | T11–T12 | 2 | 2 | No growth on cultures | None | None |
2 | Osteomyelitis/discitis, neurological deficit, and bony instability | IV antibiotics | L4–L5 | 2 | 1 (to pelvis) | No growth on cultures | Daptomycin and Zosyn, 4 wk | Doxycycline, Life |
3 | Epidural abscess and neurological deficit | Laminectomy | L3–L5 | 2 | 1 (to pelvis) | Streptococcus mitis | Ceftriaxone, 6 wk | Not available |
4 | Epidural abscess, discitis, neurological deficit, and bony instability | None | T8–T9 | 2 | 4 | MRSA | Nafcillin, 6 wk | Not available |
5 | Epidural abscess, neurological deficit, and bony instability | None | T5–T6 | 2 | 2 | MRSA | Vancomycin, 12 wk | Doxycycline, Life |
6 | Osteomyelitis, epidural abscess, neurological deficit, and bony instability | Oral fluconazole | L1–L3 | 4 | 3 | Candida | None | Fluconazole and Clindamycin, lost to follow-up |
7 | Discitis and bony instability | IV antibiotics and laminectomy | L5–S1 | 1 | 1 (to pelvis) | MRSA | Vancomycin and Daptomycin, 12 wk | Doxycycline, Life |
8 | Osteomyelitis/discitis | IV antibiotics | L2–L3 | 1 | 1 | MSSA | Ceftriaxone, 4 wk | Not available |
9 | Osteomyelitis, neurological deficit, and bony instability | IV antibiotics | L5–S1 | 1 | 1 (to pelvis) | MSSA | Vancomycin, 8 wk | Not available |
10 | Osteomyelitis/discitis and bony instability | None | T7–T8 | 2 | 2 | MRSA | Vancomycin, 8 wk | Doxycycline, Life |
11 | Osteomyelitis/discitis and neurological deficit | Bracing | L2–L3 | 1 | 1 | Streptococcus anginosus | Ceftriaxone, 6 wk | Amoxicillin, Life |
12 | Osteomyelitis and bony instability | IV antibiotics | L2–L3 | 2 | 2 | MSSA | Cefazolin, 6 wk | Doxycycline, Life |
13 | Epidural abscess, neurological deficit, and bony instability | None | T9–T10 | 3 | 3 | No growth on cultures | Vancomycin and ceftriaxone, 2 wk | None |
14 | Osteomyelitis/discitis and bony instability | IV antibiotics | T9–T10 | 3 | 2 | MRSA | Vancomycin, 8 wk | Doxycycline, Life |
15 | Epidural abscess and neurological deficit | None | T9–T10 | 3 | 3 | MRSA | Daptomycin, 8 wk | Doxycycline, Life |
16 | Osteomyelitis/discitis, neurological deficit, and bony instability | None | T9–T10 | 2 | 3 | Candida | Fluconazole, 24 wk | |
17 | Osteomyelitis, neurological deficit, and bony instability | IV antibiotics | T11–T12 | 2 | 2 | Corynebacterium | Vancomycin | Amoxicillin, Life |
18 | Osteomyelitis/discitis and bony instability | IV antibiotics | L3–L4 | 1 | 2 (to pelvis) | MSSA | Ceftriaxone | Doxycycline, Life |
19 | Discitis and epidural abscess | IV antibiotics and computed tomography-guided psoas drainage | L1–L4 | 1 | 1 | MRSA | Ceftaroline, Vancomycin | Doxycycline, Life |
20 | Epidural abscess and neurological deficit | IV antibiotics | T6–T7 | 1 | 1 | MSSA | Cefazolin | Not available |
21 | Osteomyelitis, epidural abscess, and neurological deficit | None | T11–L1 | 1 | 1 | Streptococcus anginosus | Penicillin, Vancomycin | Amoxicillin, 24 wk |
22 | Discitis and neurological deficit | IV antibiotics | T9–T11 | 3 | 1 | Escherchia coli | Cetriaxone | Not available |
23 | Discitis, epidural abscess, neurological deficit, and bony instability | IV antibiotics | L4–L5 | 2 | 1 (to pelvis) | Klebsiella | Ertapenem, Vancomycin | Clindamycin, 52 wk |
24 | Discitis, neurological deficit, and bony instability | None | T9–T10 | 2 | 2 | Aggregobacter aphrophilus | CTX | Levofloxacin, 52 wk |
25 | Discitis and bony instability | IV antibiotics, oral fluconazole, irrigation, and debridement | T11–T12 | 2 | 2 | Candida | Fluconazole, 24 wk | |
26 | Osteomyelitis/discitis, neurological deficit, and bony instability | IV antibiotics | L2–L3 | 1 | 2 | Peptostreptococcus | Ertapenem | Not available |
27 | Osteomyelitis and neurological deficit | IV antibiotics | T11–T12 | 2 | 2 | MRSA | Ceftaroline | Bactrim, lost to follow-up |
Abbreviations: IV, intravenous; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-susceptible Staphylococcus aureus.