Table 1

Summary of current FDA-approved cervical disc arthroplasty devices with clinical and radiographic image examples.

Implant Name and ManufacturerPicture and X-ray of ImplantArticulating MaterialsTheoretical Center of
Rotation		Internal FixationYear Approved by FDAFDA Approved for:
Single/2 Level 		MRI Compatiblea:Available Disc Heights (mm)Commercially Available
Prestige LP—Medtronic Embedded Image Embedded Image Titanium ceramicSuperior vertebraScrews2014YesYesYes5, 6, 7, and 8Yes
Bryan—Medtronic Embedded Image Embedded Image Titanium-aluminum-vanadium alloyWithin implantMilled bone2009YesNoYes8.5Yes
Prodisc-C—Centinel Spine Embedded Image Embedded Image Cobalt-chrome-molybdenumInferior vertebraKeels2007YesNoYes5, 6, and 7Yes
M6—Spinal Kinetics Embedded Image Embedded Image Titanium-aluminum-vanadium alloyInferior vertebraSerrated fins2019YesNoConditional

  • Maximum spatial gradient magnetic field of <4000 Gauss/cm (40 T/m)b

6 and 7Yes
Simplify—Simplify Medical Embedded Image Embedded Image Polyetheretherketone and porous titanium plasma coatingVariableSerrated fins and teeth2020YesYesYes4, 5, and 6Yes
Secure-C—Globus Medical Embedded Image Embedded Image Cobalt-chrome-molybdenum“Natural”Serrated keels2012YesNoConditionalb

  • Maximum spatial gradient magnetic field of <4000 Gauss/cm (40 T/m)

7, 8, 9, 10, 11, and 12Yes
Mobi-C—Zimmer Biomet Embedded Image Embedded Image Cobalt-chrome-molybdenum, plasma sprayed titanium, and hydroxyapatite coatingSelf-adjusting mobile coreTeeth2013YesYesConditionalb

  • Maximum spatial gradient magnetic field of <970 Gauss/cm (9.7 T/m)

5, 6, and 7Yes

  • Abbreviations: FDA, Food and Drug Administration; MRI, magnetic resonance imaging.

  • ↵a MRI conditional are devices that are MRI safe under a very specific set of conditions/MRI settings provided in the labeling.

  • ↵b Patients can safely undergo magnetic resonance (MR) scanning based on the following MR specifications established through nonclinical testing: (1) static magnetic field of 1.5 and 3.0 Tesla only, (2) specified maximum spatial gradient magnetic field (implant specific), and (3) maximum MR system reported, whole body averaged specific absorption rate of 2 W/kg in normal operating mode.