Table 3

Mean (SD) pain visual analog scale scores in mm for the 4 treatment groups across time.

Treatment GroupLow-Dose IDCT
N = 20
High-Dose IDCT
N = 20
Vehicle
N = 10
Placebo
N = 10
Day 160.5 (13.4)64.9 (14.7)62.6 (10.0)63.3 (17.1)
Week 446.8 (24.2))45.2 (27.3)51.8 (20.9)45.9 (15.4
Week 1234.8 (23.3)30.3 (24.8)40.4 (23.6)45.6 (16.7)
Week 2631.5 (19.9)32.1 (23.7)41.1 (18.2)29.6 (8.7)
Week 52a 36.6 (23.8)23.8 (21.2)30.0 (24.2)38.6 (23.9)
Week 7837.3 (24.6)25.9 (26.2)34.9 (21.5)31.6 (21.2)
Week 10428.1 (21.9)26.7 (26.6)25.2 (17.5)44.8 (18.8)
  • Abbreviation: IDCT, injectable disc cell therapy.

  • a Primary endpoint (N’s = 18, 17, 9, and 7 for the 4 groups, respectively).