Summary of current FDA-approved cervical disc arthroplasty devices with clinical and radiographic image examples.
Implant Name and Manufacturer | Picture and X-ray of Implant | Articulating Materials | Theoretical Center of Rotation | Internal Fixation | Year Approved by FDA | FDA Approved for: Single/2 Level | MRI Compatiblea: | Available Disc Heights (mm) | Commercially Available | |||
Prestige LP—Medtronic |
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![]() | Titanium ceramic | Superior vertebra | Screws | 2014 | Yes | Yes | Yes | 5, 6, 7, and 8 | Yes | |
Bryan—Medtronic |
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![]() | Titanium-aluminum-vanadium alloy | Within implant | Milled bone | 2009 | Yes | No | Yes | 8.5 | Yes | |
Prodisc-C—Centinel Spine |
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![]() | Cobalt-chrome-molybdenum | Inferior vertebra | Keels | 2007 | Yes | No | Yes | 5, 6, and 7 | Yes | |
M6—Spinal Kinetics |
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![]() | Titanium-aluminum-vanadium alloy | Inferior vertebra | Serrated fins | 2019 | Yes | No | Conditional
| 6 and 7 | Yes | |
Simplify—Simplify Medical |
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![]() | Polyetheretherketone and porous titanium plasma coating | Variable | Serrated fins and teeth | 2020 | Yes | Yes | Yes | 4, 5, and 6 | Yes | |
Secure-C—Globus Medical |
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![]() | Cobalt-chrome-molybdenum | “Natural” | Serrated keels | 2012 | Yes | No | Conditionalb
| 7, 8, 9, 10, 11, and 12 | Yes | |
Mobi-C—Zimmer Biomet |
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![]() | Cobalt-chrome-molybdenum, plasma sprayed titanium, and hydroxyapatite coating | Self-adjusting mobile core | Teeth | 2013 | Yes | Yes | Conditionalb
| 5, 6, and 7 | Yes |
Abbreviations: FDA, Food and Drug Administration; MRI, magnetic resonance imaging.
↵a MRI conditional are devices that are MRI safe under a very specific set of conditions/MRI settings provided in the labeling.
↵b Patients can safely undergo magnetic resonance (MR) scanning based on the following MR specifications established through nonclinical testing: (1) static magnetic field of 1.5 and 3.0 Tesla only, (2) specified maximum spatial gradient magnetic field (implant specific), and (3) maximum MR system reported, whole body averaged specific absorption rate of 2 W/kg in normal operating mode.