Table 2

The demographic characteristics of the patient population of the included studies.

AuthorsNo. of PatientsMean AgeMean
Follow-Up		Site of InvolvementClinical and Radiological Presentation
Peng et al10 97.7 y30.3 moCervical—2
Thoracic—5
Lumbar—1
Sacral—1		8 patients (88.9%) patients had neurological symptoms
Jiang et al11 518 y7.2 yMultiple sitesNeck pain and low back pain
2 patients had neurological symptoms
Abdelaal et al12 12—solitary site
3—multifocal sites		Not provided49 moCervical—5
Thoracic—8
Lumbar—4		Anterior wedging: 2
Vertebra plana picture:13
Nakamura et al13 5—solitary site
8—multifocal sites		3.6 y10.2 yCervical—3
Thoracic—3
T-L junction—2
Lumbar—5		Not provided
Zhou et al14 31
(23 —solitary spinal site; 8—multifocal skeletal sites)		8.8 ± 2.8 y2.9 ± 1.1 yCervical—8
Thoracic—11
Lumbar—4		Back pain or neck pain according to the location of the tumor
Neurological symptoms: 8 patients
Local kyphosis: 4 patients
Zheng et al15 9 patients66.7 mo26.7 moThoracic—4
Lumbar—5		Vertebral collapse more than 50%
Zheng et al16 15 patients74.3 ± 38.8 mo2.9 yThoracic—9
Lumbar—6

  1. Vertebral collapse more than 50%

  2. Asymmetrical destruction of vertebral body with collapse less than 50%

Zhong et al17 19 patients9.9 ± 3.1 y36.4 ± 13.7 moC1–C2: 7 patients
C3–C7: 12 patients		1. Neck movements restriction
2. Neck pain
3. Neurological symptoms
4. Torticollis