Clinical characteristics of 1734 patients undergoing surgical treatment for L5 to S1 isthmic spondylolisthesis with minimum of 2-year follow-up.
| Characteristic | ALIF (n = 578) | TLIF (n = 1156) | P | ||
| n | % | n | % | ||
| Age, y, mean ± SD | 48.9 ± 13.1 | 49.1 ± 12.8 | 0.847 | ||
| Sex, woman | 325 | 56.3% | 595 | 51.4% | 0.087 |
| Region | |||||
| Midwest | 180 | 31.1% | 458 | 39.5% | 0.008 |
| Northeast | 98 | 17.0% | 151 | 13.1% | |
| South | 206 | 35.7% | 349 | 30.2% | |
| West | 94 | 16.2% | 199 | 17.2% | |
| Comorbidities | |||||
| Charlson Comorbidity Index, mean ± SD | 1.3 ± 1.6 | 1.3 ± 1.6 | 0.521 | ||
| BMI 30–40 | 46 | 7.9% | 106 | 9.1% | 0.488 |
| BMI 40+ | 20 | 3.5% | 62 | 5.4% | 0.150 |
| Smoke | 132 | 22.8% | 242 | 21.0% | 0.841 |
| Chronic pulmonary disease | 122 | 21.1% | 239 | 20.7% | 0.872 |
| Peripheral vascular disease | 41 | 7.1% | 73 | 6.3% | 0.679 |
| Diabetes mellitus | 112 | 19.4% | 264 | 22.8% | 0.142 |
| Hyperlipidemia | 212 | 36.7% | 467 | 40.4% | 0.201 |
| Hypertension | 240 | 41.5% | 539 | 46.6% | 0.075 |
| Hypothyroidism | 98 | 17.0% | 168 | 14.5% | 0.245 |
| Congestive heart failure | 13 | 2.2% | 22 | 1.9% | 0.740 |
| Coronary artery disease | 48 | 8.3% | 110 | 9.5% | 0.497 |
| Renal disease | 23 | 4.0% | 52 | 4.5% | 0.748 |
| Depression | 179 | 31.0% | 368 | 31.8% | 0.764 |
| Rheumatoid arthritis | 19 | 3.3% | 31 | 2.7% | 0.618 |
| Osteoporosis | 76 | 13.1% | 168 | 14.5% | 0.592 |
| Surgical details | |||||
| Access surgeon use | 215 | 37.2% | 0 | 0.0% | - |
| Allograft | 276 | 47.8% | 516 | 44.6% | 0.263 |
| Bone morphogenetic protein | 52 | 9.0% | 50 | 4.3% | <0.001 |
Abbreviations: ALIF, anterior lumbar interbody fusion; BMI, body mass index; TLIF, transforaminal lumbar interbody fusion.
Note: Data presented as n and % unless otherwise noted. Boldface indicates statistical significance with P < 0.05.