Table 7

Complication rates in PLF patients starting NSAIDs use 90 d to 1 y with different dispensing intervals.

Complication	NSAIDs Days Dispensed (1–30 d)
Complication	N Control	N Intervention	OR	CI Lower	CI Upper	P
Readmission	47,754	7219	1.021	0.909	1.148	0.721
Pseudoarthrodesis and hardware failure	47,754	7219	1.039	0.981	1.100	0.196
Wound complications	47,754	7219	0.952	0.878	1.033	0.239

Complication	NSAIDs Days Dispensed (31–90 d)
Complication	N Control	N Intervention	OR	CI Lower	CI Upper	P
Readmission	47,754	3314	1.083	0.921	1.273	0.333
Pseudoarthrodesis and hardware failure	47,754	3314	1.096	1.009	1.190	0.030
Wound complications	47,754	3314	0.977	0.871	1.096	0.688

Complication	NSAIDs Days Dispensed (91–180 d)
Complication	N Control	N Intervention	OR	CI Lower	CI Upper	P
Readmission	47,754	1898	0.999	0.803	1.242	0.990
Pseudoarthrodesis and hardware failure	47,754	1898	1.154	1.035	1.287	0.010
Wound complications	47,754	1898	1.064	0.920	1.229	0.405

Complication	NSAIDs Days Dispensed (181–365 d)
Complication	N Control	N Intervention	OR	CI Lower	CI Upper	P
Readmission	47,754	1193	1.358	1.069	1.725	0.012
Pseudoarthrodesis and hardware failure	47,754	1193	1.104	0.964	1.264	0.152
Wound complications	47,754	1193	1.299	1.097	1.537	0.020

Abbreviations: NSAIDs, nonsteroidal anti-inflammatory drugs; PLF, posterior lumbar fusion.
Note: Bold values indicate a significance at a Bonferroni-adjusted P value of ≤0.01.