Table 1

Mesenchymal stem cell death after 24 hour exposure to vancomycin.

Vancomycin Concentration (μg/mL)% Cell Death compared to 0 μg/mLp-Value
0 (control)---
400 9.43%0.047
1600 13.79%0.0047
3200 19.35%<0.0001
4800 13.58%0.0043
6400 24.82%<0.0001
12800 51.83%<0.0001

  • Statistically significant cell death was seen at all tested doses of vancomycin. Increased doses of of vancomycin were associated with increased cell death.