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CC BY-NC-ND 4.0 · Asian J Neurosurg 2021; 16(04): 725-731
DOI: 10.4103/ajns.AJNS_345_20
Original Article

Long-term clinicoradiological outcomes of cervical fusion with polyether ether ketone versus cervical disc arthroplasty in a double-blinded randomized control trial

Vijay Gupta
Department of Neurosurgery, National Institute of Medical Sciences (NIMS) University, Jaipur, Rajasthan
,
Neeraj Basantani
1   Department of Neurosurgery, Ram Raghu Hospital, Agra, Uttar Pradesh
,
Ajay Carvalho
2   Department of Neurosurgery, Armed Forces Medical College and Command Hospital Southern Command, Pune, Maharashtra
,
Ekata Gupta
3   Health Care Clinic, Jaipur, Rajasthan
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Introduction: In this double-blinded randomized controlled trial, we compare the long-term clinicoradiological effects of anterior cervical discectomy and fusion with polyether ether ketone implant (ACDF with PEEK) versus artificial cervical disc (cervical disc arthroplasty [CDA]) in patients with single and bilevel cervical degenerative disc disease (CDDD). Aims: We aimed to compare the pain scores, cervical kinematics, and radiological outcomes in patients undergoing CDA and ACDF for single and bilevel CDDD over 5 years. Settings and Design: This study was carried out from 2010 to 2019 in the Neurosurgery Department of a Tertiary Care Hospital attached to a Medical College in India. Subjects and Methods: We enrolled 30 patients in each group. Clinical and radiological assessments were carried out for all patients over a period of 5 years. Statistical Analysis Used: Wilcoxon Signed-rank test, Mann–Whitney U-test, and Fischer's exact test were used for comparing the preoperative and follow-uP values. R software version 3.6.0 was used for statistical analysis. Results: A significant improvement in the cervical range of motion, sagittal range of motion (ROM), and functional spinal unit (FSU) was observed in the CDA group at final follow-up, while the PEEK group reported a significant decrease in the ROM and FSU and the difference between the two groups was also found to be statistically significant. Conclusions: When assessed over 5 years following surgery, we found CDA to be superior with respect to ROM, FSU, overall cervical alignment, and maintenance of disc height when compared to ACDF with PEEK implant.

Key-words:

Anterior cervical discectomy and fusion - cervical disc arthroplasty - cervical arthrodesis - cervical arthroplasty - cervical degenerative disc disease - polyether ketone

Financial support and sponsorship

Nil.




Publication History

Received: 11 August 2020

Accepted: 06 October 2020

Article published online:
16 August 2022

© 2021. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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