Increased rate of arthrodesis with strut grafting after multilevel anterior cervical decompression

Spine (Phila Pa 1976). 2002 Jan 15;27(2):146-51. doi: 10.1097/00007632-200201150-00005.

Abstract

Study design: Reconstruction techniques after multilevel anterior cervical decompression were retrospectively compared.

Objective: To compare radiographic and clinical outcomes of multiple interbody grafting with strut grafting.

Summary of background data: Previous studies have reported lower fusion rates for anterior cervical decompressions reconstructed with multiple interbody grafts as opposed to a single strut graft, although these techniques have never been directly compared in a consecutive series of patients who underwent surgery by a single surgeon.

Methods: Over a 20-year period, 190 patients underwent anterior cervical decompression and autogenous grafting without internal fixation and were followed for an average of 68 months. There were 98 two-level and 33 three-level discectomies with interbody grafting. These were compared with 16 one-level, 21 two-level, 20 three-level, and 2 four-level corpectomies with strut grafting. Radiographic and clinical outcomes were compared between the groups by chi2 and rank-sum analysis, respectively.

Results: Of the 59 patients who underwent strut grafting, 55 achieved a solid arthrodesis (93%), as compared with 87 of the 131 patients who underwent multiple interbody grafting (66%) (P = 0.0002). There were six cases of graft displacement or extrusion among the 59 patients who had strut grafts, as compared with no graft-related complications among the 131 patients who had interbody grafts (P < 0.0001). More "good" and "excellent" clinical outcomes were found among patients who underwent strut-grafting (88% vs 84%), although the difference was not statistically significant (P = 0.73). However, patients with a pseudarthrosis had significantly poorer clinical outcomes (P < 0.0001).

Conclusions: A much higher fusion rate was achieved after corpectomy and strut grafting than after multilevel discectomy and interbody grafting. Although there were strut graft-related complications, four of these six complications occurred among patients who had a postlaminectomy kyphosis. Because pseudarthrosis resulted in poorer clinical outcomes, strut grafting should be considered after multilevel anterior cervical decompression to increase the likelihood of successful fusion.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arthrodesis / methods*
  • Bone Transplantation / methods*
  • Cervical Vertebrae / pathology*
  • Cervical Vertebrae / surgery*
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Orthopedic Fixation Devices
  • Radiculopathy / diagnosis
  • Radiculopathy / pathology
  • Radiculopathy / surgery
  • Spinal Osteophytosis / diagnosis
  • Spinal Osteophytosis / surgery*
  • Spinal Osteophytosis / therapy*
  • Transplantation, Autologous
  • Treatment Outcome