User profiles for Byumsu Kim

Byumsu Kim

PhD, Mechanical and Aerospace Engineering
Verified email at cornell.edu
Cited by 40

Pathomechanism and biomechanics of degenerative disc disease: features of healthy and degenerated discs

S Kirnaz, C Capadona, M Lintz, B Kim… - International journal of …, 2021 - ijssurgery.com
The human intervertebral disc (IVD) is a complex organ composed of fibrous and cartilaginous
connective tissues, and it serves as a boundary between 2 adjacent vertebrae. It provides …

Instabilities induced by mechanical loading determine the viability of chondrocytes grown on porous scaffolds

B Kim, N Bouklas, I Cohen, LJ Bonassar - Journal of Biomechanics, 2023 - Elsevier
Tissue-engineered cartilage constructs have shown promise to treat focal cartilage defects in
multiple clinical studies. Notably, products in clinical use or in late-stage clinical trials often …

[HTML][HTML] Understanding the influence of local physical stimuli on chondrocyte behavior

B Kim, LJ Bonassar - … of Cartilage and Osteoarthritis: A Tribute to Alan …, 2023 - Springer
Investigating the mechanobiology of chondrocytes Chondrocyte is challenging due to the
complex micromechanical environment of cartilage Cartilage tissue Tissue . The innate zonal …

Finite element modeling to predict the influence of anatomic variation and implant placement on performance of biological intervertebral disc implants

M Koga, B Kim, M Lintz, S Kirnaz, JL Goldberg… - JOR …, 2023 - Wiley Online Library
Background Tissue‐engineered intervertebral disc (TE‐IVD) constructs are an attractive
therapy for treating degenerative disc disease and have previously been investigated in vivo in …

Microscale strain concentrations in tissue-engineered osteochondral implants are dictated by local compositional thresholds and architecture

B Kim, TAN Kelly, HJ Jung, OS Beane… - Journal of …, 2024 - Elsevier
Tissue-engineered osteochondral implants manufactured from condensed mesenchymal
stem cell bodies have shown promise for treating focal cartilage defects. Notably, such …

The influence of chondrocyte source on the manufacturing reproducibility of human tissue engineered cartilage

JM Middendorf, N Diamantides, B Kim, C Dugopolski… - Acta Biomaterialia, 2021 - Elsevier
Multiple human tissue engineered cartilage constructs are showing promise in advanced
clinical trials but identifying important measures of manufacturing reproducibility remains a …

79 Flexible Support Materials Maintain Disc Height and Support the Formation of Hydrated Tissue Engineered Intervertebral Discs in Vivo

A Fidai, B Kim, M Lintz, P Gadjradj, S Kirnaz… - Journal of Clinical and …, 2024 - cambridge.org
OBJECTIVES/GOALS: We evaluated the long-term success of tissue engineered intervertebral
discs (TE-IVDs) cultured in flexible (FPLA) or stiff (PLA) support materials, hypothesizing …

Compression Induces Chondrocyte Detachment from Porous Scaffolds in Tissue-Engineered Cartilage Constructs

B Kim, N Bouklas, I Cohen, LJ Bonassar - Available at SSRN 4553935 - papers.ssrn.com
Tissue engineering techniques have demonstrated clinical efficacy in healing focal cartilage
defects. Engineered cartilage products that are commercially available or in clinical trials …

[BOOK][B] Electromechanobiology of Cartilage and Osteoarthritis: A Tribute to Alan Grodzinsky on His 75th Birthday

BK Connizzo, L Han, RL Sah - 2023 - library.oapen.org
This is an open access book. In honor of his 75th birthday, we reflect on the impact of the
pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth …

Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model

AP Peredo, SE Gullbrand, CS Friday… - Science Translational …, 2023 - science.org
Conventional microdiscectomy treatment for intervertebral disc herniation alleviates pain
but does not repair the annulus fibrosus, resulting in a high incidence of recurrent herniation …