User profiles for Charisse Capadona

Charisse Capadona

Memorial Sloan Kettering Cancer Center
Verified email at mskcc.org
Cited by 152

Fundamentals of intervertebral disc degeneration

S Kirnaz, C Capadona, T Wong, JL Goldberg… - World neurosurgery, 2022 - Elsevier
Lumbar disc degeneration is one of the leading causes of chronic low back pain. The
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …

Pathomechanism and biomechanics of degenerative disc disease: features of healthy and degenerated discs

S Kirnaz, C Capadona, M Lintz, B Kim… - International journal of …, 2021 - ijssurgery.com
The human intervertebral disc (IVD) is a complex organ composed of fibrous and cartilaginous
connective tissues, and it serves as a boundary between 2 adjacent vertebrae. It provides …

Innovative biological treatment methods for degenerative disc disease

S Kirnaz, S Singh, C Capadona, M Lintz, JL Goldberg… - World Neurosurgery, 2022 - Elsevier
Low back pain is the leading cause of work absences and years lived with disability, and it
is often associated with degenerative disc disease. In recent years, biological treatment …

[HTML][HTML] T099: High efficacy and durability of second-line therapy with pembrolizumab, gemcitabine, vinorelbine, and liposomal doxorubicin in the phase II study for …

…, L Perez, S Sohail, A Santarosa, C Capadona… - …, 2022 - journals.lww.com
Results: Part I included 39 pts evaluable for toxicity and 38 evaluable for efficacy. Among 38
evaluable pts, CR and overall response rates (ORR) were 95% and 100%. 36 pts …

Immune Signature of Pembrolizumab Plus Gemcitabine, Vinorelbine, and Liposomal Doxorubicin As Second-Line Therapy for Relapsed or Refractory Classical …

…, T Davey, A Santarosa, L Perez, C Capadona… - Blood, 2022 - ashpublications.org
Introduction: In our phase II study (Moskowitz AJ et al, JCO 2021), pembrolizumab plus
gemcitabine, vinorelbine, and liposomal doxorubicin (P-GVD) was found to be highly effective as …

Attention-based Shape-Deformation Networks for Artifact-Free Geometry Reconstruction of Lumbar Spine from MR Images

L Qian, J Chen, L Ma, T Urakov, W Gu… - arXiv preprint arXiv …, 2024 - arxiv.org
Lumbar disc degeneration, a progressive structural wear and tear of lumbar intervertebral
disc, is regarded as an essential role on low back pain, a significant global health concern. …