User profiles for D. Joshua Cohen

David Cohen

Virginia Commonwealth University
Verified email at vcu.edu
Cited by 1384

Detection and localization of surgically resectable cancers with a multi-analyte blood test

JD Cohen, L Li, Y Wang, C Thoburn, B Afsari… - Science, 2018 - science.org
Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can
detect eight common cancer types through assessment of the levels of circulating proteins and …

[HTML][HTML] Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer

J Tie, JD Cohen, K Lahouel, SN Lo… - … England Journal of …, 2022 - Mass Medical Soc
Background The role of adjuvant chemotherapy in stage II colon cancer continues to be
debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor …

Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

…, V Silvestri, K Schipper, JD Cohen… - Proceedings of the …, 2016 - National Acad Sciences
Recent genomic studies challenge the conventional model that each metastasis must arise
from a single tumor cell and instead reveal that metastases can be composed of multiple …

[HTML][HTML] Cancer-associated mutations in endometriosis without cancer

…, R Alhassan, A Wang, Y Wang, JD Cohen… - … England Journal of …, 2017 - Mass Medical Soc
Background Endometriosis, defined as the presence of ectopic endometrial stroma and
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic pain …

Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

JD Cohen, AA Javed, C Thoburn… - Proceedings of the …, 2017 - National Acad Sciences
The earlier diagnosis of cancer is one of the keys to reducing cancer deaths in the future. Here
we describe our efforts to develop a noninvasive blood test for the detection of pancreatic …

Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention

…, CS Adonizio, HJ Hwang, K Lahouel, JD Cohen… - Science, 2020 - science.org
INTRODUCTION The goal of earlier cancer detection is to identify the disease at a stage
when it can be effectively treated, thereby offering the patient a better chance of long-term …

Circulating tumor DNA analyses as markers of recurrence risk and benefit of adjuvant therapy for stage III colon cancer

J Tie, JD Cohen, Y Wang, M Christie, K Simons… - JAMA …, 2019 - jamanetwork.com
Importance Adjuvant chemotherapy in patients with stage III colon cancer prevents recurrence
by eradicating minimal residual disease. However, which patients remain at high risk of …

Bone marrow stromal cells are sensitive to discrete surface alterations in build and post‐build modifications of bioinspired Ti6Al4V 3D‐printed in vitro testing …

MB Berger, DJ Cohen, K Snyder, J Sions… - … Research Part B …, 2023 - Wiley Online Library
… Boyan, Zvi Schwartz, and D. Joshua Cohen receive grant support from Medtronic, Curiteva,
and Pascal Medical. Barbara D. Boyan is vice-chair of the CCAM Board and John Sions and …

[BOOK][B] A robust and verifiable cryptographically secure election scheme

JD Cohen, MJ Fischer - 1985 - academia.edu
Cryptographic techniques are becoming important for a wide variety of distributed
computing tasks where the processing agents are either unreliable or untrustworthy.(Cf.[DiHe76],[…

Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study

J Tie, JD Cohen, Y Wang, L Li, M Christie, K Simons… - Gut, 2019 - gut.bmj.com
Objective For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy
selection following surgery remains a major clinical dilemma. Here, we investigated the …