Many approaches are used to repair skeletal defects in reconstructive orthopaedic surgery,
and bone grafting is involved in virtually every procedure. The type of bone graft used …

With the exception of blood, bone is the most frequently transplanted tissue in humans. F'More
than 100,000 bone graft or bone implant procedures are performed in the United States …

Bone morphogenetic proteins (BMPs) have been the subject of considerable research for
several decades. The academic chronicle began in 1965 with Dr. Marshall Urist’s discovery of …

Study Design. A prospective randomized controlled human clinical pilot trial. Objectives. To
determine the feasibility of using rhBMP-2/collagen as a substitute for autogenous bone graft …

Study Design. A prospective randomized clinical study was conducted. Objective. To
determine whether the dose and carrier that were successful in rhesus monkeys could induce …

Study Design. Retrospective review of a large series of patients who underwent spinal surgery
at a single institution during a 10-year period. Objectives. To further clarify the frequency …

Study Design. A retrospective chart review was conducted for 112 patients who underwent
revision posterior lumbar spine decompression, fusion, and segmental instrumentation. …

Background: Recombinant human bone morphogenetic protein-2 soaked into an absorbable
collagen sponge (rhBMP-2/ACS) has been shown in a nonhuman primate study and in a …

Anterior lumbar interbody arthrodesis is commonly performed for conditions involving infection,
deformity, and instability. The purpose of this investigation was to determine the effective …

At least 250,000 spinal fusions are performed in the United States each year, nearly all requiring
implantation of bone graft mate-The preferred technique for most of these operations is …