… Jason Inzana is supported by an NSF graduate research fellowship (2012116002). The
content is solely the responsibility of the authors and does not necessarily represent the official …

Additive manufacturing, also known as 3D printing, has emerged over the past 3 decades
as a disruptive technology for rapid prototyping and manufacturing. Vat polymerization, …

Orthopaedic devices are the most common surgical devices associated with implant-related
infections and Staphylococcus aureus (S. aureus) is the most common causative pathogen …

Surgical implant-associated bone infections (osteomyelitis) have severe clinical and
socioeconomic consequences. Treatment of chronic bone infections often involves antibiotics given …

Fracture nonunions develop in 10%–20% of patients with fractures, resulting in prolonged
disability. Current data suggest that bone union during fracture repair is achieved via …

Mice are the small animal model of choice in biomedical research due to the low cost and
availability of genetically engineered lines. However, the devices utilized in current mouse …

Finite element analysis is commonly used to assist in the development and evaluation of
orthopedic devices. The physics of these models are simplified through approximations that …

Introduction The obesity epidemic has resulted in a large increase in type 2 diabetes (T2D).
While some secondary complications of T2D are well recognized and their cellular and …

Background Lead (Pb) exposure and obesity are co-occurring risk factors for decreased bone
mass in the young, particularly in low socioeconomic communities. Objectives The goal of …

Biphasic calcium phosphate scaffolds formed via three dimensional (3D) printing technology
to exhibit porosity and chemical resorbability to promote osseointegration often lack the …