Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium

S Kitajima, S Takuma, M Morimoto - Experimental animals, 1999 - jstage.jst.go.jp
In this study we examined changes in colonic mucosal permeability induced by dextran
sulfate sodium (DSS) during the acute phase of mouse colitis. To induce colitis, the mice were …

Histological analysis of murine colitis induced by dextran sulfate sodium of different molecular weights

S Kitajima, S Takuma, M Morimoto - Experimental animals, 2000 - jstage.jst.go.jp
In this study, we examined the relationship between the molecular weight of dextran sulfate
sodium (DSS) and the features of colitis in a DSS-induced mouse model of human ulcerative …

Dextran sodium sulfate-induced colitis in germ-free IQI/Jic mice

S Kitajima, M Morimoto, E Sagara, C SHIMIZU… - Experimental …, 2001 - jstage.jst.go.jp
This study presents a histological examination of dextran sodium sulfate (DSS)-induced colitis
in germ-free (GF) mice. A comparison of the pathology between GF and conventionalized …

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance

…, M Shiomi, B Zhang, S Kitajima, M Morimoto… - The American journal of …, 2005 - Elsevier
C-reactive protein (CRP) is frequently deposited in the lesions of the arterial intima; however,
the origin and pathological significance of CRP in these lesions are not completely …

Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits

…, E Liu, Y Yu, S Kitajima, T Koike, Y Jin, M Morimoto… - Circulation, 2006 - Am Heart Assoc
Background— Macrophage metalloelastase (matrix metalloproteinase [MMP]-12) is upregulated
in atherosclerotic lesions and aneurysm; thus, increased MMP-12 activity may play an …

Increased expression of vascular endothelial growth factor in kidney leads to progressive impairment of glomerular functions

E Liu, M Morimoto, S Kitajima, T Koike… - Journal of the …, 2007 - journals.lww.com
Vascular endothelial growth factor (VEGF) is an important mediator in maintaining normal
kidney functions. In addition, several lines of evidence suggest that upregulation of VEGF in …

Tissue distribution of dextran sulfate sodium (DSS) in the acute phase of murine DSS-induced colitis

…, S TAKUMA, M MORIMOTO - Journal of veterinary …, 1999 - jstage.jst.go.jp
In the present study, we examined histochemically the tissue distribution of dextran sulfate
sodium (DSS) in the acute phase of murine colitis induced by administering DSS in the …

Matrix metalloproteinase 12 accelerates the initiation of atherosclerosis and stimulates the progression of fatty streaks to fibrous plaques in transgenic rabbits

…, J Fan, S Shimajiri, S Kitajima, M Morimoto… - The American journal of …, 2008 - Elsevier
Whether fatty streaks are directly followed by fibrous plaque formation in atherosclerosis
remains controversial. Disruption of the basement membrane and elastic layers is thought to be …

Human C-reactive protein does not promote atherosclerosis in transgenic rabbits

…, Y Yu, K Nishijima, J Zhang, Y Ozaki, M Morimoto… - Circulation, 2009 - Am Heart Assoc
Background— Although there is a statistically significant association between modestly
raised baseline plasma C-reactive protein (CRP) values and future cardiovascular events, the …

Hyperphagia and obesity in rats with bilateral ibotenic acid-induced lesions of the ventromedial hypothalamic nucleus

N Shimizu, Y Oomura, CR Plata-Salamán, M Morimoto - Brain research, 1987 - Elsevier
Macro-electrophoretic applications of the cellular neurotoxin ibotenic acid into the
ventromedial hypothalamic nucleus (VMH) resulted in hyperphagia and obesity in male rats. …