The mechanics of single cell and collective migration of tumor cells
M Lintz, A Muñoz… - Journal of …, 2017 - asmedigitalcollection.asme.org
Metastasis is a dynamic process in which cancer cells navigate the tumor microenvironment,
largely guided by external chemical and mechanical cues. Our current understanding of …
largely guided by external chemical and mechanical cues. Our current understanding of …
Biologic Annulus Fibrosus Repair: A Review of Preclinical In Vivo Investigations
Lower back pain, the leading cause of workplace absences and disability, is often attributed
to intervertebral disc degeneration, in which nucleus pulposus (NP) herniates through …
to intervertebral disc degeneration, in which nucleus pulposus (NP) herniates through …
Pathomechanism and biomechanics of degenerative disc disease: features of healthy and degenerated discs
The human intervertebral disc (IVD) is a complex organ composed of fibrous and cartilaginous
connective tissues, and it serves as a boundary between 2 adjacent vertebrae. It provides …
connective tissues, and it serves as a boundary between 2 adjacent vertebrae. It provides …
Molecular transport in articular cartilage—what have we learned from the past 50 years?
CD DiDomenico, M Lintz, LJ Bonassar - Nature Reviews Rheumatology, 2018 - nature.com
Developing therapeutic molecules that target chondrocytes and locally produced inflammatory
factors within arthritic cartilage is an active area of investigation. The extensive studies …
factors within arthritic cartilage is an active area of investigation. The extensive studies …
[BOOK][B] Tissue engineering strategies for total disc replacement: structure and mechanical function of the Intervertebral disc
M Lintz - 2021 - search.proquest.com
Degenerative disc disease (DDD) is implicated as one of the primary causes of lower back
pain (LBP), the leading cause of disability worldwide. This degeneration is characterized by …
pain (LBP), the leading cause of disability worldwide. This degeneration is characterized by …
The degenerative impact of hyperglycemia on the structure and mechanics of developing murine intervertebral discs
M Lintz, RE Walk, SY Tang, LJ Bonassar - JOR spine, 2022 - Wiley Online Library
Introduction Diabetes has long been implicated as a major risk factor for intervertebral disc (IVD)
degeneration, interfering with molecular signaling and matrix biochemistry, which …
degeneration, interfering with molecular signaling and matrix biochemistry, which …
Innovative biological treatment methods for degenerative disc disease
Low back pain is the leading cause of work absences and years lived with disability, and it
is often associated with degenerative disc disease. In recent years, biological treatment …
is often associated with degenerative disc disease. In recent years, biological treatment …
Finite element modeling to predict the influence of anatomic variation and implant placement on performance of biological intervertebral disc implants
Background Tissue‐engineered intervertebral disc (TE‐IVD) constructs are an attractive
therapy for treating degenerative disc disease and have previously been investigated in vivo in …
therapy for treating degenerative disc disease and have previously been investigated in vivo in …
Basic Science of Resident Stem Cells
LA Fortier, M Lintz - Operative Techniques in Sports Medicine, 2020 - Elsevier
A natural reservoir of stem/progenitor cells exists in most tissues of the musculoskeletal
system including cartilage, meniscus, ligament, tendon, bone, muscle, and the synovial …
system including cartilage, meniscus, ligament, tendon, bone, muscle, and the synovial …
79 Flexible Support Materials Maintain Disc Height and Support the Formation of Hydrated Tissue Engineered Intervertebral Discs in Vivo
OBJECTIVES/GOALS: We evaluated the long-term success of tissue engineered intervertebral
discs (TE-IVDs) cultured in flexible (FPLA) or stiff (PLA) support materials, hypothesizing …
discs (TE-IVDs) cultured in flexible (FPLA) or stiff (PLA) support materials, hypothesizing …
