Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline
CJ Padilla, ME Harrigan, H Harris, JM Schwab… - Geroscience, 2021 - Springer
Pathological age-related loss of skeletal muscle strength and mass contribute to impaired
physical function in older adults. Factors that promote the development of these conditions …
physical function in older adults. Factors that promote the development of these conditions …
Lesion level–dependent systemic muscle wasting after spinal cord injury is mediated by glucocorticoid signaling in mice
ME Harrigan, AR Filous, CP Vadala, A Webb… - Science Translational …, 2023 - science.org
An incomplete mechanistic understanding of skeletal muscle wasting early after spinal cord
injury (SCI) precludes targeted molecular interventions. Here, we demonstrated systemic …
injury (SCI) precludes targeted molecular interventions. Here, we demonstrated systemic …
[PDF][PDF] Discovery of stromal regulatory networks that suppress ras-sensitized epithelial cell proliferation
Mesodermal cells signal to neighboring epithelial cells to modulate their proliferation in both
normal and disease states. We adapted a Caenorhabditis elegans organogenesis model to …
normal and disease states. We adapted a Caenorhabditis elegans organogenesis model to …
[HTML][HTML] Assessing rat forelimb and hindlimb motor unit connectivity as objective and robust biomarkers of spinal motor neuron function
ME Harrigan, AR Filous, AP Tosolini, R Morris… - Scientific Reports, 2019 - nature.com
Sensitive and objective biomarkers of neuronal injury, degeneration, and regeneration can
help facilitate translation of experimental findings into clinical testing. Whereas measures of …
help facilitate translation of experimental findings into clinical testing. Whereas measures of …
Demineralized Bone Matrix and Fibers in Spinal Fusion
JL Wang, RG Eaton, ME Harrigan, V Munjal… - International Journal of …, 2023 - ijssurgery.com
Formation of bony fusion after arthrodesis depends on osteoinduction, osteoconduction, and
osteogenesis. Traditionally, the patient’s own bone, or autograft, has been used to provide …
osteogenesis. Traditionally, the patient’s own bone, or autograft, has been used to provide …
Correction to: profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline
CJ Padilla, ME Harrigan, H Harris, JM Schwab… - GeroScience, 2021 - Springer
Aged rats demonstrate significant deficits in neuromuscular junction transmission ab.
Repetitive nerve stimulation demonstrated significant reduction of compound muscle action …
Repetitive nerve stimulation demonstrated significant reduction of compound muscle action …
Lesion level-dependent glucocorticoid dysregulation exacerbates systemic muscle wasting during the acute phase of paraplegic rodent spinal cord injury
ME Harrigan - 2022 - rave.ohiolink.edu
Recently an increased appreciation for the systemic consequences of spinal cord injury (SCI)
has re-emerged. These pathophysiological processes provide novel therapeutic targets, …
has re-emerged. These pathophysiological processes provide novel therapeutic targets, …
Novel stromal-derived oncogenic signals enhance Ras-mediated cell proliferation
M Harrigan - 2015 - kb.osu.edu
… Finally, I would like to thank my family, especially my parents Christopher Harrigan and
Heidi Beke-Harrigan, and friends for their unwavering support. I would not be where I am today, …
Heidi Beke-Harrigan, and friends for their unwavering support. I would not be where I am today, …
Ischemic stroke due to blunt traumatic cerebrovascular injury
MR Harrigan - Stroke, 2020 - Am Heart Assoc
354 Stroke January 2020 motion causing stretching of the artery, or a direct blow to the
artery, may produce intimal tears and expose subendothelial collagen, resulting in platelet …
artery, may produce intimal tears and expose subendothelial collagen, resulting in platelet …
Me, myself, and I: A systematic review of cystic fibrosis and self‐concept
Given extensive pertinent disease factors and evolving medical treatments, this systematic
review explores qualitative and quantitative cystic fibrosis (CF) research surrounding self‐…
review explores qualitative and quantitative cystic fibrosis (CF) research surrounding self‐…