Background: Drinking during pregnancy has been associated with learning disabilities in
affected offspring. At present, there are no clinically effective pharmacotherapeutic …

Background Studies in vitro demonstrate that neuronal membrane/lipid rafts (MLRs)
establish cell polarity by clustering progrowth receptors and tethering cytoskeletal machinery …

Many children adversely affected by maternal drinking during pregnancy cannot be identified
early in life using current diagnostic criteria for fetal alcohol spectrum disorder (FASD). We …

Abstract Effects of withdrawal from ethanol drinking in chronic intermittent ethanol vapor (CIE)-exposed
dependent rats and air-exposed nondependent rats on proliferation and survival …

Alcohol use disorder currently affects approximately 18 million Americans, with at least half
of these individuals having significant cognitive impairments subsequent to their chronic …

Prolonged alcohol exposure has been previously shown to impair the structure and function
of the hippocampus, although the underlying structural and biochemical alterations …

Adult neurogenesis in the dentate gyrus (DG) is strongly influenced by drug-taking behavior
and may have a role in the etiology of drug-seeking behavior. However, mechanistic studies …

Background Prenatal ethanol ( E t OH ) and prenatal stress have both been independently
shown to induce learning deficits and anxiety behavior in adult offspring. However, the …

The need for effective treatments for addiction and dependence to the illicit stimulant
methamphetamine in primary care settings is increasing, yet no effective medications have been …

Background Anterior lumbar interbody fusion (ALIF) is utilized in symptomatic spinal disc
destabilization due to degenerative lumbar disc disease, isthmic and degenerative …