[HTML][HTML] Amyloid-β peptides and tau protein as biomarkers in cerebrospinal and interstitial fluid following traumatic brain injury: a review of experimental and clinical …

PP Tsitsopoulos, N Marklund - Frontiers in neurology, 2013 - frontiersin.org
Traumatic brain injury (TBI) survivors frequently suffer from life-long deficits in cognitive
functions and a reduced quality of life. Axonal injury, observed in many severe TBI patients, …

[HTML][HTML] Current opportunities for clinical monitoring of axonal pathology in traumatic brain injury

PP Tsitsopoulos, S Abu Hamdeh, N Marklund - Frontiers in neurology, 2017 - frontiersin.org
Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly
resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces …

A systematic review on the prevalence of preoperative and postoperative depression in lumbar fusion

…, GA Alexiou, S Voulgaris, PP Tsitsopoulos - Journal of Clinical …, 2022 - Elsevier
Background Depression and Degenerative Spine Disease (DSD) frequently co-exist. Pooled
prevalence estimates of depression before and after lumbar fusion surgery has not been …

Evaluation of pullout strength and failure mechanism of posterior instrumentation in normal and osteopenic thoracic vertebrae

O Paxinos, PP Tsitsopoulos, MR Zindrick… - … of Neurosurgery: Spine, 2010 - thejns.org
Object There is limited data on the pullout strength of spinal fixation devices in the thoracic
spine among individuals with different bone quality. An in vitro biomechanical study on the …

The current significance of the FOUR score: a systematic review and critical analysis of the literature

DM Anestis, PP Tsitsopoulos, CA Tsonidis… - Journal of the …, 2020 - Elsevier
Background The Full Outline of Un-Responsiveness Score (FOURs) is a scale for clinical
assessment of consciousness that was introduced to overcome disadvantages of the widely …

[HTML][HTML] The neurological wake-up test does not alter cerebral energy metabolism and oxygenation in patients with severe traumatic brain injury

K Skoglund, L Hillered, K Purins, PP Tsitsopoulos… - Neurocritical care, 2014 - Springer
Background The neurological wake-up test (NWT) is used to monitor the level of consciousness
in patients with traumatic brain injury (TBI). However, it requires interruption of sedation …

[HTML][HTML] Increasing motivation and engagement in neurosurgery for medical students through practical simulation-based learning

J Hanrahan, M Sideris, PP Tsitsopoulos… - Annals of Medicine and …, 2018 - Elsevier
Background Simulation-based learning (SBL) is an essential adjunct to modern surgical
education. Our study aimed to evaluate the educational benefit and motivational impact of a …

Surgical treatment of patients with unilateral cerebellar infarcts: clinical outcome and prognostic factors

PP Tsitsopoulos, L Tobieson, P Enblad… - Acta neurochirurgica, 2011 - Springer
Background There are limited data on the long-term outcome and on factors influencing the
prognosis in patients with cerebellar infarcts treated with surgical decompression. Methods …

A systematic review on the outcome of intramedullary spinal cord cavernous malformations

…, LT Meszaros, DM Anestis, PP Tsitsopoulos - European Spine …, 2022 - Springer
Purpose This study aimed to investigate the neurological outcome, trends and sequelae
following surgical or conservative treatment of intramedullary spinal cord cavernous …

Prognostic factors and long-term outcome following surgical treatment of 76 patients with spontaneous cerebellar haematoma

PP Tsitsopoulos, L Tobieson, P Enblad… - Acta neurochirurgica, 2012 - Springer
Background Although large spontaneous cerebellar haematomas are associated with high
mortality, surgical treatment may be life-saving. We evaluated the clinical outcome and …