Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
PCH Hsieh, VFM Segers, ME Davis, C MacGillivray… - Nature medicine, 2007 - nature.com
An emerging concept is that the mammalian myocardium has the potential to regenerate,
but that regeneration might be too inefficient to repair the extensive myocardial injury that is …
but that regeneration might be too inefficient to repair the extensive myocardial injury that is …
Loss of gut microbiota alters immune system composition and cripples postinfarction cardiac repair
Background: The impact of gut microbiota on the regulation of host physiology has recently
garnered considerable attention, particularly in key areas such as the immune system and …
garnered considerable attention, particularly in key areas such as the immune system and …
Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction
ME Davis, PCH Hsieh, T Takahashi… - Proceedings of the …, 2006 - National Acad Sciences
Strategies for cardiac repair include injection of cells, but these approaches have been
hampered by poor cell engraftment, survival, and differentiation. To address these shortcomings …
hampered by poor cell engraftment, survival, and differentiation. To address these shortcomings …
Anterior lumbar interbody fusion in comparison with transforaminal lumbar interbody fusion: implications for the restoration of foraminal height, local disc angle, lumbar …
PC Hsieh, TR Koski, BA O'Shaughnessy… - … of Neurosurgery: Spine, 2007 - thejns.org
Object A primary consideration of all spinal fusion procedures is restoration of normal anatomy,
including disc height, lumbar lordosis, foraminal decompression, and sagittal balance. …
including disc height, lumbar lordosis, foraminal decompression, and sagittal balance. …
FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction
Mammalian cardiomyocytes have limited proliferation potential, and acutely injured mammalian
hearts do not regenerate adequately. Instead, injured myocardium develops fibrosis and …
hearts do not regenerate adequately. Instead, injured myocardium develops fibrosis and …
[HTML][HTML] Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers
PCH Hsieh, ME Davis, J Gannon… - The Journal of …, 2006 - Am Soc Clin Investig
Endothelial cells can protect cardiomyocytes from injury, but the mechanism of this protection
is incompletely described. Here we demonstrate that protection of cardiomyocytes by …
is incompletely described. Here we demonstrate that protection of cardiomyocytes by …
Endothelial-cardiomyocyte interactions in cardiac development and repair
PCH Hsieh, ME Davis, LK Lisowski… - Annu. Rev. Physiol …, 2006 - annualreviews.org
▪ Abstract Communication between endothelial cells and cardiomyocytes regulates not only
early cardiac development but also adult cardiomyocyte function, including the contractile …
early cardiac development but also adult cardiomyocyte function, including the contractile …
Custom design of the cardiac microenvironment with biomaterials
ME Davis, PCH Hsieh, AJ Grodzinsky… - Circulation research, 2005 - Am Heart Assoc
Many strategies for repairing injured myocardium are under active investigation, with some
early encouraging results. These strategies include cell therapies, despite little evidence of …
early encouraging results. These strategies include cell therapies, despite little evidence of …
Intraoperative neurophysiological monitoring during spine surgery: a review
…, D Jeyanandarajan, C Hansen, G Zada, PC Hsieh - Neurosurgical …, 2009 - thejns.org
Spinal surgery involves a wide spectrum of procedures during which the spinal cord, nerve
roots, and key blood vessels are frequently placed at risk for injury. Neuromonitoring …
roots, and key blood vessels are frequently placed at risk for injury. Neuromonitoring …
Biodegradable core/shell fibers by coaxial electrospinning: processing, fiber characterization, and its application in sustained drug release
C Wang, KW Yan, YD Lin, PCH Hsieh - Macromolecules, 2010 - ACS Publications
Solutions of two biodegradable polymers, that is, poly(dl-lactic acid) (PDLLA) and poly(3-hydroxy
butyrate) (PHB), were individually delivered to the inner and outer channel of a coaxial-…
butyrate) (PHB), were individually delivered to the inner and outer channel of a coaxial-…