User profiles for PAUL M. ARNOLD
Paul M. ArnoldChairman, Department of Neurosurgery Verified email at carle.com Cited by 19582 |
Efficacy and safety of surgical decompression in patients with cervical spondylotic myelopathy: results of the AOSpine North America prospective multi-center study
Background: Cervical spondylotic myelopathy is the leading cause of spinal cord
dysfunction worldwide. The objective of this study was to evaluate the impact of surgical …
dysfunction worldwide. The objective of this study was to evaluate the impact of surgical …
Acute Cervical Traumatic Spinal Cord Injury: MR Imaging Findings Correlated with Neurologic Outcome—Prospective Study with 100 Consecutive Patients1
Purpose: To prospectively evaluate whether quantitative and qualitative magnetic resonance
(MR) imaging assessments after spinal cord injury (SCI) correlate with patient neurologic …
(MR) imaging assessments after spinal cord injury (SCI) correlate with patient neurologic …
A clinical practice guideline for the management of patients with degenerative cervical myelopathy: recommendations for patients with mild, moderate, and severe …
Study Design: Guideline development. Objectives: The objective of this study is to develop
guidelines that outline how to best manage (1) patients with mild, moderate, and severe …
guidelines that outline how to best manage (1) patients with mild, moderate, and severe …
Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury
BW Festoff, S Ameenuddin, PM Arnold… - Journal of …, 2006 - Wiley Online Library
Minocycline, a clinically used tetracycline for over 40 years, crosses the blood–brain barrier
and prevents caspase up‐regulation. It reduces apoptosis in mouse models of Huntington's …
and prevents caspase up‐regulation. It reduces apoptosis in mouse models of Huntington's …
Perioperative and delayed complications associated with the surgical treatment of cervical spondylotic myelopathy based on 302 patients from the AOSpine North …
MG Fehlings, JS Smith, B Kopjar, PM Arnold… - Journal of neurosurgery …, 2012 - thejns.org
Object Rates of complications associated with the surgical treatment of cervical spondylotic
myelopathy (CSM) are not clear. Appreciating these risks is important for patient counseling …
myelopathy (CSM) are not clear. Appreciating these risks is important for patient counseling …
Navigation and robotics in spinal surgery: where are we now?
Spine surgery has experienced much technological innovation over the past several decades.
The field has seen advancements in operative techniques, implants and biologics, and …
The field has seen advancements in operative techniques, implants and biologics, and …
Apoptosis in cellular compartments of rat spinal cord after severe contusion injury
Following a controlled, severe contusion lesion to the lower thoracic spinal cord in adult rats,
we found that apoptosis occurred in cells located in both gray and white matter. This …
we found that apoptosis occurred in cells located in both gray and white matter. This …
Assessment of two thoracolumbar fracture classification systems as used by multiple surgeons
KB Wood, G Khanna, AR Vaccaro, PM Arnold… - JBJS, 2005 - journals.lww.com
Background: The reproducibility and repeatability of modern systems for classification of
thoracolumbar injuries have not been sufficiently studied. We assessed the interobserver and …
thoracolumbar injuries have not been sufficiently studied. We assessed the interobserver and …
Prevention of surgical site infection in spine surgery
…, JW Savage, AR Vaccaro, K Radcliff, PM Arnold… - …, 2017 - journals.lww.com
BACKGROUND: Spine surgery is complicated by an incidence of 1% to 9% of surgical site
infection (SSI). The most common organisms are gram-positive bacteria and are endogenous…
infection (SSI). The most common organisms are gram-positive bacteria and are endogenous…
A clinical practice guideline for the management of patients with acute spinal cord injury and central cord syndrome: recommendations on the timing (≤ 24 hours …
Objective: To develop recommendations on the timing of surgical decompression in patients
with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic …
with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic …