Aseptic loosening and osteolysis are currently the most common causes of failure of total joint
replacements. Osteolysis is initiated by a macrophage response to wear debris, resulting …

BACKGROUND CONTEXT: Disc degeneration (DD) is a multifaceted chronic process that
alters the structure and function of the intervertebral discs and can lead to painful conditions. …

Discogenic back pain is multifactorial; hence, physicians often struggle to identify the underlying
source of the pain. As a result, discogenic back pain is often hard to treat—even more …

OBJECTIVE Enhanced recovery after surgery (ERAS) and multimodal analgesia are
established care models that minimize perioperative opioid consumption and promote positive …

Objective. To assess the effect glycemic control has on perioperative morbidity and mortality
in patients undergoing elective degenerative lumbar spine surgery. Summary of …

Study Design Systematic literature review and meta-analysis of studies published in English.
Objective This study evaluated differences in outcome variables between percutaneous …

Study Design. A retrospective cohort study of prospectively collected data. Objective. The
aim of this study was to describe the development of and early experience with an evidence-…

Background context Posterior cervical foraminotomy (PCF) with or without microdiscectomy (posterior
cervical discectomy [PCD]) is a frequently used surgical technique for cervical …

Over the past two decades, minimally invasive surgical approaches have become increasingly
feasible, efficient and popular for the management of a wide range of spinal disorders, …

Object In recent years, there has been increased interest in the use of cervical disc replacement
(CDR) as an alternative to anterior cervical discectomy and fusion (ACDF). While ACDF …