Study Design. Systematic review and modified Delphi technique. Objective. To use an
evidence-based medicine process using the best available literature and expert opinion …

Question Should patients with newly-diagnosed metastatic brain tumors undergo stereotactic
radiosurgery (SRS) compared with other treatment modalities? Target population These …

Purpose Standardized indications for treatment of tumor-related spinal instability are hampered
by the lack of a valid and reliable classification system. The objective of this study was to …

• Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI)
is not recommended. Clinicians considering MP therapy should bear in mind that the drug …

Object An increasing incidence of brain cancer has been reported for the last three decades.
In this study of brain cancer incidence and patient survival in the US, the authors attempt to …

Question Should patients with newly-diagnosed metastatic brain tumors undergo open surgical
resection versus whole brain radiation therapy (WBRT) and/or other treatment modalities …

Association of Neurological Surgeons and Congress of Neurological Surgeons published
the first evidence-based guidelines for the management of patients with acute cervical spinal …

Should whole brain radiation therapy (WBRT) be used as the sole therapy in patients with
newly-diagnosed, surgically accessible, single brain metastases, compared with WBRT plus …

Question Do steroids improve neurologic symptoms in patients with metastatic brain tumors
compared to no treatment? If steroids are given, what dose should be used? Comparisons …

Metastatic tumours involving the brain overshadow primary brain neoplasms in frequency
and are an important complication in the overall management of many cancers. Importantly, …