The biology of fracture healing is better understood than ever before, with advancements
such as the locking screw leading to more predictable and less eventful osseous healing. …

Purpose The purpose of the AIS is to (1) standardize careful, detailed documentation of spinal
cord injuries,(2) guide further radiographic assessment and treatment, and (3) determine …

Langerhans cell histiocytosis is a rare group of disorders without a well-understood etiology.
Known formerly as histiocytosis X, the disease has a wide spectrum of clinical presentations…

In a large cohort of osteogenesis imperfecta type V (OI type V) patients (17 individuals from
12 families), we identified the same mutation in the 5′ untranslated region (5′UTR) of the …

Study Design. Experimental animal study of convective transport in the intervertebral disc.
Objective. To quantify the effects of mechanical loading rate on net transport into the healthy …

Chronic musculoskeletal pain results from a complex interplay of mechanical, biochemical,
psychological, and social factors. Effective management is markedly different from that of …

… of MoM hip arthroplasties demonstrated cell-mediated type IV hypersensitivity/DTH reactions,
which are characterized by accumulations of periarticular monoclonal or oligoclonal T cells …

Osteogenesis imperfecta is a heritable group of collagen-related disorders that affects up to
50,000 people in the United States. Although the disease is most symptomatic in childhood, …

Background context The intervertebral disc primarily relies on trans-endplate diffusion for the
uptake of nutrients and the clearance of byproducts. In degenerative discs, diffusion is often …

Considered the father of the screw, Archimedes of Syracuse is widely regarded as having
invented the screw in the third century BCE. His published treatises on geometry were a …