[HTML][HTML] Herniated discs: when is surgery necessary?

WW Yoon, J Koch - EFORT Open Reviews, 2021 - eor.bioscientifica.com
Herniated discs: when is surgery necessary? in: EFORT Open Reviews Volume 6 Issue 6 (2021)
Jump to Content Logo Logo Logo Logo Logo Logo Sign in Create account Home Browse …

[HTML][HTML] Unilateral biportal endoscopic discectomy versus percutaneous endoscopic lumbar discectomy in the treatment of lumbar disc herniation: a retrospective …

HW Jiang, CD Chen, BS Zhan, YL Wang… - Journal of Orthopaedic …, 2022 - Springer
Background Unilateral biportal endoscopic discectomy (UBE) is a rapidly growing surgical
method that uses arthroscopic system for treatment of lumbar disc herniation (LDH), while …

[HTML][HTML] Emerging issues questioning the current treatment strategies for lumbar disc herniation

ZY Wan, H Shan, TF Liu, F Song, J Zhang, ZH Liu… - Frontiers in …, 2022 - frontiersin.org
Lumbar disc herniation is among the common phenotypes of degenerative lumbar spine
diseases, significantly affecting patients' quality of life. The practice pattern is diverse …

[HTML][HTML] Macrophage-based therapy for intervertebral disc herniation: preclinical proof-of-concept

C Ribeiro-Machado, SG Santos, IA Amaral… - NPJ Regenerative …, 2023 - nature.com
Intervertebral disc (IVD) degeneration and herniation is a leading cause of disability globally
and a large unmet clinical need. No efficient non-surgical therapy is available, and there is …

Association between chiropractic spinal manipulation and lumbar discectomy in adults with lumbar disc herniation and radiculopathy: retrospective cohort study using …

RJ Trager, CJ Daniels, JA Perez, RM Casselberry… - BMJ open, 2022 - bmjopen.bmj.com
Objectives Chiropractic spinal manipulative therapy (CSMT) and lumbar discectomy are
both used for lumbar disc herniation (LDH) and lumbosacral radiculopathy (LSR); however …

Minimally Invasive Intradiscal Delivery of BM-MSCs via Fibrous Microscaffold Carriers

P Nakielski, D Rybak… - … Applied Materials & …, 2023 - ACS Publications
Current treatments of degenerated intervertebral discs often provide only temporary relief or
address specific causes, necessitating the exploration of alternative therapies. Cell-based …

Assessment and post-intervention recovery after surgery for lumbar disk herniation based on objective gait metrics from wearable devices using the gait posture index

F Ghent, RJ Mobbs, RR Mobbs, L Sy, C Betteridge… - World neurosurgery, 2020 - Elsevier
Objective Surgery for lumbar disk herniation (LDH) presents an option for patients when
conservative measures fail. The objective of this clinical study is to investigate a novel …

Heterogeneous macrophages contribute to the pathology of disc herniation induced radiculopathy

L Jin, L Xiao, M Ding, A Pan, G Balian, SSJ Sung, XJ Li - The Spine Journal, 2022 - Elsevier
ABSTRACT BACKGROUND CONTEXT Macrophages play important roles in the
progression of intervertebral disc herniation and radiculopathy. PURPOSE To better …

Expert review with meta-analysis of randomized and nonrandomized controlled studies of Barricaid annular closure in patients at high risk for lumbar disc reherniation

LE Miller, RT Allen, B Duhon… - Expert review of medical …, 2020 - Taylor & Francis
Introduction: Patients with lumbar disc herniation and associated sciatica are often referred
for lumbar discectomy. The surgical defect in the annulus fibrosus is typically left unrepaired …

Understanding how the research question impacts trial design: Examples from discectomy trials

J Raymond, VKY Chan, TE Darsaut - Neurochirurgie, 2023 - Elsevier
Background Formulating a pertinent research question is of the utmost importance in clinical
research. An ill-conceived question may lead to an erroneous trial design, which may …