Background: Spinal fusion involves both endochondral and intramembranous bone
formation. We previously demonstrated that endochondral cartilage grafts that were derived …

Study Design. Biological augmentation spinal arthrodesis trial in athymic rats. Objective. To
assess the efficacy of tissue-engineered bone to promote L4-L5 intertransverse process …

Object Posterolateral spinal fusions are performed to treat different spinal disorders.
Autograft continues to be the gold standard; it is, however, associated with donor site …

Background: Insufficient data exist on bone graft substitute materials efficacy; two thirds lack
any clinical data., This prospective animal study identified efficacy differences among …

Background: To evaluate the comparative abilities of commercially available, viable, cellular
bone allografts to promote posterolateral spinal fusion. Methods: Human allografts …

Background: Posterolateral spinal fusion is used to treat patients with degenerative spinal
disorders. In this study, we investigated the effectiveness of a mesenchymal stem cell …

BACKGROUND CONTEXT: The athymic rat has been used to study the role of
osteoinductive products in spinal fusions. This small animal model has been advocated to …

Study Design. A posterolateral lumbar arthrodesis animal model using coralline
hydroxyapatite as a bone graft substitute. Objective. To determine the effectiveness of …

Study Design. An animal study was performed to evaluate lumbar spinal fusion
radiologically and mechanically. Objectives. To assess the efficacy of interconnected porous …

Study Design. A controlled rabbit model of lumbar posterolateral intertransverse process
arthrodesis was used to evaluate a bone graft substitute. Objective. To determine the …