Stem cells and intervertebral disc regeneration overview—what they can and can't do
Background: Low back pain (LPB) is the main cause of disability worldwide with enormous
socioeconomic burdens. A major cause of LBP is intervertebral disc degeneration (IDD): a …
socioeconomic burdens. A major cause of LBP is intervertebral disc degeneration (IDD): a …
[HTML][HTML] Application of stem cells in the repair of intervertebral disc degeneration
W Zhang, T Sun, Y Li, M Yang, Y Zhao, J Liu… - Stem cell research & …, 2022 - Springer
Intervertebral disc degeneration (IDD) is a common disease that increases with age, and its
occurrence is stressful both psychologically and financially. Stem cell therapy for IDD is …
occurrence is stressful both psychologically and financially. Stem cell therapy for IDD is …
Cell therapy for treatment of intervertebral disc degeneration: a systematic review
HJ Meisel, N Agarwal, PC Hsieh, A Skelly… - Global spine …, 2019 - journals.sagepub.com
Study Design: Systematic review. Objective: To review, critically appraise, and synthesize
evidence on use of cell therapy for intervertebral disc repair. Methods: A systematic search …
evidence on use of cell therapy for intervertebral disc repair. Methods: A systematic search …
Stem cell approaches to intervertebral disc regeneration: obstacles from the disc microenvironment
F Wang, R Shi, F Cai, YT Wang… - Stem Cells and …, 2015 - liebertpub.com
Intervertebral disc (IVD) degeneration results in segmental instability and irritates neural
compressive symptoms, such as low back pain and motor deficiency. The transplanting of …
compressive symptoms, such as low back pain and motor deficiency. The transplanting of …
[HTML][HTML] A review: Methodologies to promote the differentiation of mesenchymal stem cells for the regeneration of intervertebral disc cells following intervertebral disc …
T Ohnishi, K Homan, A Fukushima, D Ukeba, N Iwasaki… - Cells, 2023 - mdpi.com
Intervertebral disc (IVD) degeneration (IDD), a highly prevalent pathological condition
worldwide, is widely associated with back pain. Treatments available compensate for the …
worldwide, is widely associated with back pain. Treatments available compensate for the …
[HTML][HTML] Concerns about cell therapy for intervertebral disc degeneration
B Peng, Y Li - NPJ Regenerative medicine, 2022 - nature.com
Low back pain is a very common symptom in people all over the world, which is now the
leading cause of disability worldwide 1, 2. Although the specific cause of low back pain is …
leading cause of disability worldwide 1, 2. Although the specific cause of low back pain is …
Stem cell therapy for intervertebral disc regeneration: obstacles and solutions
D Sakai, GBJ Andersson - Nature Reviews Rheumatology, 2015 - nature.com
Intervertebral disc (IVD) degeneration is frequently associated with low back and neck pain,
which accounts for disability worldwide. Despite the known outcomes of the IVD …
which accounts for disability worldwide. Despite the known outcomes of the IVD …
[HTML][HTML] Clinical development of regenerative medicine targeted for intervertebral disc disease
Low back pain is critical health, social, and economic issue in modern societies. This
disease is often associated with intervertebral disc degeneration; however, contemporary …
disease is often associated with intervertebral disc degeneration; however, contemporary …
Stem cell regeneration of degenerated intervertebral discs: current status
SM Richardson, JA Hoyland - Current pain and headache reports, 2008 - Springer
Low back pain (LBP) is one of the most common musculoskeletal conditions, and
intervertebral disc (IVD) degeneration is associated with most cases. Although many …
intervertebral disc (IVD) degeneration is associated with most cases. Although many …
[HTML][HTML] Cell therapy for intervertebral disc repair: clinical perspective
Low back pain is the main cause of disability and is associated with intervertebral disc
degeneration. Contemporary treatments are limited to palliative therapeutics or aggressive …
degeneration. Contemporary treatments are limited to palliative therapeutics or aggressive …