PT - JOURNAL ARTICLE AU - OU-YANG, DAVID AU - MOLDAVSKY, MARK AU - WESSELL, NOLAN AU - BROOKS, DAINA M. AU - TITANTI, MARIANO AU - MATHEIS, ERIKA A. AU - BUCKLEN, BRANDON S. AU - PATEL, VIKAS TI - Evaluation of Spinous Process Tethering at the Proximal End of Rigid Constructs: In Vitro Range of Motion and Intradiscal Pressure at Instrumented and Adjacent Levels AID - 10.14444/7076 DP - 2020 Aug 01 TA - International Journal of Spine Surgery PG - 571--579 VI - 14 IP - 4 4099 - https://www.ijssurgery.com/content/14/4/571.short 4100 - https://www.ijssurgery.com/content/14/4/571.full SO - Int J Spine Surg2020 Aug 01; 14 AB - Background Adult spinal deformity surgery requires use of long thoracolumbar instrumentation, which is associated with risk of postoperative proximal junctional kyphosis (PJK). Tethering has been used in spinal surgery but not around the spinous process (SP) in the context of preventing PJK.Methods Researchers applied a nondestructive hybrid loading protocol to 7 T8–L2 cadaveric specimens in flexion-extension, lateral bending, and axial rotation (AR). A rigid construct (pedicle screws and rods) and 1- and 2-level SP constructs were tested, as was a hand-tie technique. SP tethering (SPT) constructs use clamps on both sides of the SP; SPT helix constructs use 1 clamp and wrap around the SP.Results All tether constructs showed greater motion at the instrumented level and less motion at adjacent levels compared to rigid constructs. In AR, 1- and 2-level SPT constructs restricted first instrumented level motion to a greater extent when compared with other tether constructs (P ≤ .05). Passing the band through the T10 SP did not produce significant biomechanical differences compared to passing it through the T9–T10 interspinous ligament (P > .05). Hand-tied constructs demonstrated more motion compared to tensioned constructs (P > .05). Intradiscal pressure results corroborated motion data.Conclusions SPT at the proximal end of a rigid construct produced more favorable biomechanical outcomes at instrumented and adjacent levels than were seen with a completely rigid construct. Clinical research is needed to determine whether these methods reduce the risk of PJK among patients.Level of Evidence 3.Clinical Relevance This work sheds light on the biomechanical stability of proximal tethering constructs in an effort to enhance the surgeon's ability to reduce rates of proximal junctional kyphosis and failure in thoracolumbar spinal fusion surgery.