The increasing prevalence of spinal disorders worldwide necessitates advanced treatments,
particularly interbody fusion for severe cases that are unresponsive to non-surgical …

Spinal injuries or diseases necessitate effective fusion solutions, and common clinical
approaches involve autografts, allografts, and various bone matrix products, each with …

Background Spinal implant failure is associated with prolonged patient suffering, high costs
for the medical device industry, and a high economic burden for the health care system. Pre …

Objective To evaluate the interbody fusion efficacy and biocompatibility of a graft-free cage
made of polyetheretherketone/calcium silicate composite/porous tantalum (PEEK/CS/pTa …

Background: Spinal fusion is a common procedure for which bone grafting is a critical
component. Although iliac crest (separate incision autograft) is typically referred to as the …

Bi-phasic calcium phosphates (BCPs) are considered prominent candidate materials for the
fabrication of bone graft substitutes. Currently, supplemental cation-doping is suggested as …

Degenerative spine disease is increasing in prevalence as the global population ages,
indicating a need for targeted therapies and continued innovations. While autograft and …

Degenerative spinal pathology is a widespread medical issue, and spine fusion surgeries
are frequently performed. In this study, we fabricated an injectable bioactive click chemistry …

Abstract Purpose of the Study The objective of this prospective, parallel, randomized, single-
center study is to evaluate the clinical success of a commercial ceramic bone graft substitute …

Background Autologous bone grafts are currently the standard in orthopedic surgery despite
limited donor sources and the prevalence of donor site morbidity. Other alternatives such as …