Epidemiology reports state temporomandibular joint disorders (TMD) affect up to 25% of the
population, yet their etiology and progression are poorly understood. As a result, treatment …

Background Minimally invasive surgical fusion of the sacroiliac (SI) joint using machined solid
triangular titanium plasma spray (TPS) coated implants has demonstrated positive clinical …

Patients suffering from damaged or diseased fibrocartilages currently have no effective long-term
treatment options. Despite their potential, engineered tissues suffer from inferior …

The knee meniscus, intervertebral disc, and temporomandibular joint (TMJ) disc all possess
complex geometric shapes and anisotropic matrix organization. While these characteristics …

The objective of this study was to improve the biomechanical properties of engineered
neotissues through promoting the development of collagen cross-links. It was hypothesized that …

The development of functionally equivalent fibrocartilage remains elusive despite efforts to
engineer tissues such as knee meniscus, intervertebral disc and temporomandibular joint disc…

Background An aging society and concomitant rise in the incidence of impaired bone health
have led to the need for advanced osteoconductive spinal implant surfaces that promote …

Tissue-engineered musculoskeletal soft tissues typically lack the appropriate mechanical
robustness of their native counterparts, hindering their clinical applicability. With structure and …

Background Overall survival (OS) has traditionally been the primary end point in studies
evaluating the clinical benefit of first-line chemotherapy in metastatic, locally advanced, or …

In the particularly active and continually aging society of the United States, injuries and
deterioration of the joints are commonplace. Whether they are sports related or result from …