Article Figures & Data
Tables
- Table 1
Distribution of baseline comorbidities in the ACS-NSQIP database, comprising a modified CCI.32
CCI CHF Peripheral Vascular Disease Cerebrovascular Injury COPD Diabetes Hemiplegia End-Stage Renal Failure Ascites/ varices Disseminated Cancer N 21 27 140 373 1103 62 6 1 14 % .4 0.5 2.4 6.3 18.7 1.1 0.1 .0 0.2 - Table 2
Univariate associations for diabetes presence at baseline with individual procedure-related complications represented in the ACS-NSQIP database. “Yes” diabetes group includes both treatment regimens (insulin [ID-DM] and non-insulin [NI-DM]). Statistically significant differences at p<0.05 are bolded.
Variable Diabetes Presence P-values for Group Comparisons NO-DM(n=4801) NI-DM (n=722) ID-DM (n=381) NO-DM to NI-DM NO-DM to ID-DM NI-DM to ID-DM NO-DM to DM Age 59.42 (11.80) 64.33 (10.24) 62.69 (10.22) <0.001 <0.001 0.012 <0.001 BMI (kg/m2) 28.66 (6.71) 32.37 (7.26) 32.72 (8.47) <0.001 <0.001 0.472 <0.001 BMI≥30 1762 (36.7%) 428 (59.3%) 235 (61.7%) <0.001 <0.001 .239 <0.001 BMI >40 234 (4.9%) 96 (13.3%) 58(15.2%) <0.001 <0.001 .215 <0.001 Smoking Hx 1443 (30.1%) 144 (19.9%) 75 (19.7%) <0.001 <0.001 .493 <0.001 Pulmonary Comorbidity 297 (6.2%) 48 (6.6%) 36 (9.4%) 0.341 0.011 0.062 0.049 Cardiac Comorbidity 168 (3.5%) 40 (5.5%) 27 (7.1%) 0.007 0.001 0.186 <0.001 - Table 3
Multivariate analysis for impact of diabetes on intra- and peri-operative patient outcomes.
Outcome Measures (OR [95% CI], p-value) Complication (Y/N) LOS (Y/N) ID-DM + ND-DM 1.67 (2.22-1.25) p<0.001 1.88 (2.26-1.88), p<0.001 ID-DM 0.492 (0.75-0.32), p=0.001 0.342 (0.46-0.25), p<0.001 ND-DM 0.73 (1.21-0.44), p=0.225 0.510 (0.72-0.36), p<0.001 - Table 4
Association of Diabetes Presence (ID-DM and NI-DM) with Individual Complications (Non-insulin- vs. Insulin-Dependent Diabetes).
Complication Diabetes Presence p-value No (n=4801) Yes (n=1103) Wound 0.6% 0.8% 0.194 Deep Incisional SSI 0.5% 0.3% 0.884 Organ/Space SSI 0.2% 0.3% .212 Wound Disruption 0.2% 0.1% 0.762 Pneumonia 1.1% 12.1 0.014 Unplanned Intubation 0.9% 2.2% 0.004 Pulmonary Embolism 0.5% 0.6% 0.747 Ventilator > 48 Hours 0.7% 1.8 <0.001 Progressive Renal Insufficiency 0.1% 0.0% 0.788 Urinary Tract Infection 1.2% 2.4% 0.030 Stroke/CVA 0.1% 0.2% 0.958 Peripheral Nerve Injury 0.1% 0.1% 0.854 Cardiac Arrest Requiring CPR 0.3% 0.6% 0.348 Myocardial Infarction 0.2% 0.5% 0.150 Bleeding Transfusions 2.5% 4.2% 0.009 Graft/Prosthesis/Flap Failure 0.0% 0.1% 0.113 DVT/Thrombophlebitis 0.7% 1.5% 0.07 Sepsis 0.6% 0.8% 0.640 Septic Shock 0.2% 0.7% 0.081 - Table 5
Association of Type of Diabetes with Individual Complications (Non-insulin- vs. Insulin-Dependent Diabetes).
Complication NI-DM (n=722) ID-DM (n=381) p-value Wound 0.5% 1.6% <0.000 Deep Incisional SSI 0.3% 0.5% 1.000 Organ/Space SSI 0.0% 0.3% 0.334 Wound Disruption 0.3% 0.0% 1.000 Pneumonia 2.3% 2.9% 0.783 Unplanned Intubation 1.5% 3.1% 0.278 Pulmonary Embolism 0.9% 0.3% 0.307 Ventilator > 48 Hours 1.4% 2.7% 0.250 Urinary Tract Infection 2.0% 2.9% 0.588 Stroke/CVA 0.3% 0.0% 0.554 Peripheral Nerve Injury 0.0% 0.3% 0.334 Cardiac Arrest Requiring
CPR1.5% 2.1% 1.000 Myocardial Infarction 0.0% 0.3% 1.000 Bleeding Transfusions 4.7% 5.2% 0.838 Graft/Prosthesis/Flap Failure 0.3% 0.0% 1.000 DVT/Thrombophlebitis 1.8% 1.5% 1.000 Sepsis 1.0% 1.5% 0.692 Septic Shock 0.5% 0.5% 1.000
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