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Characteristic Depression Cohort (n = 23) Nondepression Cohort (n = 49) P Age, y, mean 48.4 53.2 0.062 Sex, female) 52.2% 46.9% 0.802 BMI, mean 31.1 30.1 0.673 Comorbidities Diabetes 13.0% 24.5% 0.358 Hypertension 26.1% 53.1% 0.043 Hyperlipidemia 13.0% 51.0% 0.002 Rheumatologic disorder 17.4% 16.3% 0.786 Alcohol abuse 13.0% 10.2% 0.721 Tobacco abuse 13.0% 8.2% 0.515 ACDF 1-level 47.8% 40.8% 0.575 2-level 43.5% 38.8% 0.704 3-level 8.7% 20.4% 0.315 Data presented as % unless otherwise noted. Boldface indicates statistically significant findings.
ACDF, anterior cervical discectomy and fusion; BMI, body mass index.
- Table 2
Mean scores on the patient-reported mental health measures (RAND and EQ-5D) and pain intensity (NDI), with comparisons before and after teh operation.
Mean Outcome Measure Preoperative Postoperative Δ P RAND: MCS overall 68.79 77.49 8.70 0.0001 EQ-5D: MHD overall 1.73 1.45 0.28 0.01 Pain intensity (NDI) overall 2.08 1.04 1.18 <0.0001 Boldface indicates statistically significant findings.
EQ-5D, EuroQol 5-dimension; MCS, Mental Composite Score; MHD, mental health domain; NDI, Neck Disability Index.
- Table 3
Results of the patient-reported mental health measures (RAND and EQ-5D) and pain intensity (NDI), with comparisons between depressed and nondepressed groups, as well as within both groups before and after the operation.
Outcome Measure Depression Cohort (n = 23) Nondepression Cohort (n = 49) P RAND MCS preoperative 48.34 78.56 <0.0001 MCS postoperative 66.78 82.63 <0.001 Mean Δ 8.70 4.04 0.001 P 0.0001 0.04 EQ-5D MHD preoperative 2.39 1.4 <0.0001 MHD postoperative 1.78 1.3 0.01 Mean Δ 0.60 0.125 0.04 P 0.01 0.28 Pain Preoperative 2.3 1.98 0.17 Postoperative 1.04 0.83 0.34 Mean Δ 1.26 1.15 0.70 P 0.001 <0.0001 Boldface indicates statistically significant findings.
EQ-5D, EuroQol 5-dimension; MCS, Mental Composite Score; MHD, mental health domain; NDI, Neck Disability Index.
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