Article Figures & Data
Tables
Funding source Positive results Negative results Mixed results Total Industry 7 0 0 7 Hospital 0 0 1 1 Foundation 1 0 0 1 Not reported 3 0 1 4 Funding source Positive results Negative results Mixed results Total Industry 13 2 3 18 Hospital 1 0 0 1 Foundation 0 1 0 1 Not reported 2 2 7 11 Graft type Advantages Disadvantages Iliac crest Large availability, low cost, growth factors, live cells Donor-site morbidity, increased blood loss, increased operative time Local bone Low cost, growth factors, live cells Limited availability Bone marrow aspirate Live cells, growth factors Needs carrier Fresh-frozen allograft Large availability, low cost, growth factors Disease transmission, inflammation, no live cells Freeze-dried allograft Large availability, low cost Brittle, no growth factors, no live cells Demineralized bone matrix Large availability, low cost Amorphous, few growth factors, no mineral portion rhBMP Large availability, potent growth factors Requires carrier, no live cells, expensive Ceramics (β-TCP and CHA) Large availability, structurally sound, low immunogenicity No live cells, no growth factors, no organic matrix
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