Bone Grafting Options for Single-Level TLIF: So Many Options, What Is the Evidence?

Enoch Kim; Matthew Brennan; Pavithra Margabandu; Nicole Oska; Maria Cielito Robles; Anneliese Rademacher; Edvin Telemi; Tarek Mansour; Victor W. Chang

doi:10.14444/8561

Research ArticleFocus Issue Article

Bone Grafting Options for Single-Level TLIF: So Many Options, What Is the Evidence?

Enoch Kim, Matthew Brennan, Pavithra Margabandu, Nicole Oska, Maria Cielito Robles, Anneliese Rademacher, Edvin Telemi, Tarek Mansour and Victor W. Chang

International Journal of Spine Surgery December 2023, 17 (S3) S53-S60; DOI: https://doi.org/10.14444/8561

Enoch Kim

1 School of Medicine, Wayne State University, Detroit, MI, USA

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For correspondence: enoch.kim@med.wayne.edu

Matthew Brennan

1 School of Medicine, Wayne State University, Detroit, MI, USA

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Pavithra Margabandu

1 School of Medicine, Wayne State University, Detroit, MI, USA

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Nicole Oska

1 School of Medicine, Wayne State University, Detroit, MI, USA

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Maria Cielito Robles

2 College of Human Medicine, Michigan State University, East Lansing, MI, USA

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Anneliese Rademacher

3 Department of Neurosurgery, Henry Ford Health Systems, Detroit, MI, USA

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Edvin Telemi

3 Department of Neurosurgery, Henry Ford Health Systems, Detroit, MI, USA

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Tarek Mansour

3 Department of Neurosurgery, Henry Ford Health Systems, Detroit, MI, USA

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Victor W. Chang

3 Department of Neurosurgery, Henry Ford Health Systems, Detroit, MI, USA

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Summary of mean fusion rate and ΔVAS-back score by graft material.

Graft Material	Mean Fusion Rate, %	ΔVAS-Back Score
Iliac crest bone graft	94.8	4.4 ± 4.1
Local autograft	92.5	3.26 ± 0.94
Allograft	96	2.86 ± 4.4
Demineralized bone matrix	92	4
Bone morphogenetic protein	92.1	-
Mesenchymal stem cell	59	-
Synthetic peptide	73.3	4.9
Ceramic	92.9	4.6 ± 2

Abbreviation: VAS, visual analog scale.

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International Journal of Spine Surgery

Vol. 17, Issue S3

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Bone Grafting Options for Single-Level TLIF: So Many Options, What Is the Evidence?

Enoch Kim, Matthew Brennan, Pavithra Margabandu, Nicole Oska, Maria Cielito Robles, Anneliese Rademacher, Edvin Telemi, Tarek Mansour, Victor W. Chang

International Journal of Spine Surgery Dec 2023, 17 (S3) S53-S60; DOI: 10.14444/8561

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Bone Grafting Options for Single-Level TLIF: So Many Options, What Is the Evidence?

Enoch Kim, Matthew Brennan, Pavithra Margabandu, Nicole Oska, Maria Cielito Robles, Anneliese Rademacher, Edvin Telemi, Tarek Mansour, Victor W. Chang

International Journal of Spine Surgery Dec 2023, 17 (S3) S53-S60; DOI: 10.14444/8561

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Keywords

bone graft
TLIF
single level
spinal fusion
autologous
ceramic
bone morphogenic protein
allograft
synthetics
mesenchymal stem cells

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